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| Apr 07 • 02:30 | San Lorenzo |  | - |  | Santos FC | 1 | : | 3 |
| Apr 08 • 02:30 | Club Libertad |  | - |  | Atlético Nacional | 1 | : | 0 |
| Apr 09 • 02:30 | Club Bolívar |  | - |  | Atlético Junior | 2 | : | 1 |
| Apr 10 • 00:15 | Independiente del Valle |  | - |  | Grêmio Porto Alegrense | 2 | : | 1 |
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| Apr 14 • 02:30 | Santos FC | | - | | San Lorenzo | 2 | : | 2 |
| Apr 15 • 00:15 | Grêmio Porto Alegrense | | - | | Independiente del Valle | 1 | : | 2 |
| Apr 15 • 02:30 | Atlético Nacional | | - | | Club Libertad | 4 | : | 1 |
| Apr 16 • 02:30 | Atlético Junior | | - | | Club Bolívar | 3 | : | 0 |
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| Group B |
Apr 21 • 00:15 | Club Always Ready |  | - |  | SC Internacional | 2 | : | 0 |
| Group B |
Apr 21 • 00:15 | Deportivo Táchira |  | - |  | Olimpia Asunción | 3 | : | 2 |
| Group C |
Apr 21 • 00:15 | Santos FC | | - |  | Barcelona SC | 0 | : | 2 |
| Group F |
Apr 21 • 00:15 | Argentinos Juniors |  | - |  | Club Nacional Montevideo | 2 | : | 0 |
| Group E |
Apr 21 • 02:30 | Sporting Cristal |  | - |  | São Paulo FC | 0 | : | 3 |
| Group G |
Apr 21 • 02:30 | Vélez Sársfield |  | - |  | Flamengo | 2 | : | 3 |
| Group C |
Apr 22 • 00:00 | The Strongest |  | - |  | Boca Juniors | 0 | : | 1 |
| Group H |
Apr 22 • 00:00 | Deportivo La Guaira |  | - |  | Atlético Mineiro | 1 | : | 1 |
| Group A |
Apr 22 • 02:00 | Independiente del Valle | | - |  | Defensa y Justicia | 1 | : | 1 |
| Group A |
Apr 22 • 02:00 | Universitario de Deportes |  | - |  | SE Palmeiras | 2 | : | 3 |
| Group E |
Apr 22 • 02:00 | CA Rentistas |  | - |  | Racing Club | 1 | : | 1 |
| Group G |
Apr 22 • 04:00 | Unión La Calera |  | - |  | LDU Quito | 2 | : | 2 |
| Group H |
Apr 22 • 04:00 | América de Cali |  | - |  | Cerro Porteño | 0 | : | 2 |
| Group D |
Apr 23 • 00:00 | Fluminense FC |  | - |  | River Plate | 1 | : | 1 |
| Group F |
Apr 23 • 02:00 | Atlético Nacional | | - |  | CD Universidad Católica | 2 | : | 0 |
| Group D |
Apr 23 • 04:00 | Atlético Junior | | - |  | Independiente Santa Fe | 1 | : | 1 |
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| Group G |
Apr 28 • 00:15 | LDU Quito | | - | | Vélez Sársfield | 3 | : | 1 |
| Group G |
Apr 28 • 00:15 | Flamengo | | - | | Unión La Calera | 4 | : | 1 |
| Group H |
Apr 28 • 00:15 | Atlético Mineiro | | - | | América de Cali | 2 | : | 1 |
| Group A |
Apr 28 • 02:30 | SE Palmeiras | | - | | Independiente del Valle | 5 | : | 0 |
| Group B |
Apr 28 • 02:30 | SC Internacional | | - | | Deportivo Táchira | 4 | : | 0 |
| Group C |
Apr 28 • 02:30 | Boca Juniors | | - | | Santos FC | 2 | : | 0 |
| Group A |
Apr 29 • 00:00 | Defensa y Justicia | | - | | Universitario de Deportes | 3 | : | 0 |
| Group F |
Apr 29 • 00:00 | Club Nacional Montevideo | | - | | Atlético Nacional | 4 | : | 4 |
| Group H |
Apr 29 • 00:00 | Cerro Porteño | | - | | Deportivo La Guaira | 0 | : | 0 |
| Group D |
Apr 29 • 02:00 | Independiente Santa Fe | | - | | Fluminense FC | 1 | : | 2 |
| Group D |
Apr 29 • 02:00 | River Plate | | - | | Atlético Junior | 2 | : | 1 |
| Group B |
Apr 29 • 04:00 | Olimpia Asunción | | - | | Club Always Ready | 2 | : | 1 |
| Group C |
Apr 29 • 04:00 | Barcelona SC | | - | | The Strongest | 4 | : | 0 |
| Group E |
Apr 30 • 00:00 | Racing Club | | - | | Sporting Cristal | 2 | : | 1 |
| Group F |
Apr 30 • 00:00 | CD Universidad Católica | | - | | Argentinos Juniors | 0 | : | 2 |
| Group E |
Apr 30 • 02:00 | São Paulo FC | | - | | CA Rentistas | 2 | : | 0 |
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| Group C |
May 05 • 00:15 | Santos FC | | - | | The Strongest | 5 | : | 0 |
| Group G |
May 05 • 00:15 | Unión La Calera | | - | | Vélez Sársfield | 0 | : | 2 |
| Group H |
May 05 • 00:15 | Atlético Mineiro | | - | | Cerro Porteño | 4 | : | 0 |
| Group A |
May 05 • 02:30 | Defensa y Justicia | | - | | SE Palmeiras | 1 | : | 2 |
| Group C |
May 05 • 02:30 | Barcelona SC | | - | | Boca Juniors | 1 | : | 0 |
| Group G |
May 05 • 02:30 | LDU Quito | | - | | Flamengo | 2 | : | 3 |
| Group A |
May 06 • 00:00 | Independiente del Valle | | - | | Universitario de Deportes | 4 | : | 0 |
| Group E |
May 06 • 00:00 | Racing Club | | - | | São Paulo FC | 0 | : | 0 |
| Group B |
May 06 • 02:00 | SC Internacional | | - | | Olimpia Asunción | 6 | : | 1 |
| Group E |
May 06 • 02:00 | CA Rentistas | | - | | Sporting Cristal | 0 | : | 0 |
| Group F |
May 06 • 04:00 | CD Universidad Católica | | - | | Club Nacional Montevideo | 3 | : | 1 |
| Group B |
May 07 • 00:00 | Club Always Ready | | - | | Deportivo Táchira | 2 | : | 0 |
| Group F |
May 07 • 00:00 | Atlético Nacional | | - | | Argentinos Juniors | 0 | : | 2 |
| Group D |
May 07 • 02:00 | Independiente Santa Fe | | - | | River Plate | 0 | : | 0 |
| Group D |
May 07 • 02:00 | Atlético Junior | | - | | Fluminense FC | 1 | : | 1 |
| Group H |
May 07 • 04:00 | Deportivo La Guaira | | - | | América de Cali | 0 | : | 0 |
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| Group B |
May 12 • 00:15 | Deportivo Táchira | | - | | SC Internacional | 2 | : | 1 |
| Group C |
May 12 • 00:15 | The Strongest | | - | | Barcelona SC | 2 | : | 0 |
| Group C |
May 12 • 00:15 | Santos FC | | - | | Boca Juniors | 1 | : | 0 |
| Group A |
May 12 • 02:30 | Independiente del Valle | | - | | SE Palmeiras | 0 | : | 1 |
| Group E |
May 12 • 02:30 | Sporting Cristal | | - | | Racing Club | 0 | : | 2 |
| Group G |
May 12 • 02:30 | Unión La Calera | | - | | Flamengo | 2 | : | 2 |
| Group E |
May 13 • 00:00 | CA Rentistas | | - | | São Paulo FC | 1 | : | 1 |
| Group F |
May 13 • 00:00 | Argentinos Juniors | | - | | CD Universidad Católica | 0 | : | 1 |
| Group D |
May 13 • 02:00 | Fluminense FC | | - | | Independiente Santa Fe | 2 | : | 1 |
| Group D |
May 13 • 02:00 | Atlético Junior | | - | | River Plate | 1 | : | 1 |
| Group H |
May 13 • 02:00 | Deportivo La Guaira | | - | | Cerro Porteño | 0 | : | 1 |
| Group A |
May 13 • 04:00 | Universitario de Deportes | | - | | Defensa y Justicia | 1 | : | 1 |
| Group F |
May 13 • 04:00 | Atlético Nacional | | - | | Club Nacional Montevideo | 0 | : | 0 |
| Group G |
May 14 • 00:00 | Vélez Sársfield | | - | | LDU Quito | 3 | : | 1 |
| Group B |
May 14 • 02:00 | Club Always Ready | | - | | Olimpia Asunción | 1 | : | 2 |
| Group H |
May 14 • 02:00 | América de Cali | | - | | Atlético Mineiro | 1 | : | 2 |
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| Group A |
May 19 • 00:15 | SE Palmeiras | | - | | Defensa y Justicia | 3 | : | 4 |
| Group C |
May 19 • 00:15 | The Strongest | | - | | Santos FC | 2 | : | 1 |
| Group F |
May 19 • 00:15 | Club Nacional Montevideo | | - | | CD Universidad Católica | 1 | : | 0 |
| Group A |
May 19 • 02:30 | Universitario de Deportes | | - | | Independiente del Valle | 3 | : | 2 |
| Group D |
May 19 • 02:30 | Fluminense FC | | - | | Atlético Junior | 1 | : | 2 |
| Group E |
May 19 • 02:30 | São Paulo FC | | - | | Racing Club | 0 | : | 1 |
| Group E |
May 20 • 00:00 | Sporting Cristal | | - | | CA Rentistas | 2 | : | 0 |
| Group G |
May 20 • 00:00 | Vélez Sársfield | | - | | Unión La Calera | 2 | : | 1 |
| Group D |
May 20 • 02:00 | River Plate | | - | | Independiente Santa Fe | 2 | : | 1 |
| Group G |
May 20 • 02:00 | Flamengo | | - | | LDU Quito | 2 | : | 2 |
| Group H |
May 20 • 02:00 | Cerro Porteño | | - | | Atlético Mineiro | 0 | : | 1 |
| Group B |
May 20 • 04:00 | Deportivo Táchira | | - | | Club Always Ready | 7 | : | 2 |
| Group H |
May 20 • 04:00 | América de Cali | | - | | Deportivo La Guaira | 3 | : | 1 |
| Group F |
May 21 • 00:00 | Argentinos Juniors | | - | | Atlético Nacional | 1 | : | 0 |
| Group B |
May 21 • 02:00 | Olimpia Asunción | | - | | SC Internacional | 0 | : | 1 |
| Group C |
May 21 • 02:00 | Boca Juniors | | - | | Barcelona SC | 0 | : | 0 |
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| Group D |
May 26 • 00:15 | River Plate | | - | | Fluminense FC | 1 | : | 3 |
| Group D |
May 26 • 00:15 | Independiente Santa Fe | | - | | Atlético Junior | 0 | : | 0 |
| Group E |
May 26 • 02:30 | São Paulo FC | | - | | Sporting Cristal | 3 | : | 0 |
| Group E |
May 26 • 02:30 | Racing Club | | - | | CA Rentistas | 3 | : | 0 |
| Group H |
May 26 • 02:30 | Cerro Porteño | | - | | América de Cali | 1 | : | 0 |
| Group H |
May 26 • 02:30 | Atlético Mineiro | | - | | Deportivo La Guaira | 4 | : | 0 |
| Group B |
May 27 • 00:00 | Olimpia Asunción | | - | | Deportivo Táchira | 6 | : | 2 |
| Group B |
May 27 • 00:00 | SC Internacional | | - | | Club Always Ready | 0 | : | 0 |
| Group C |
May 27 • 02:00 | Boca Juniors | | - | | The Strongest | 3 | : | 0 |
| Group C |
May 27 • 02:00 | Barcelona SC | | - | | Santos FC | 3 | : | 1 |
| Group F |
May 27 • 04:00 | Club Nacional Montevideo | | - | | Argentinos Juniors | 2 | : | 0 |
| Group F |
May 27 • 04:00 | CD Universidad Católica | | - | | Atlético Nacional | 2 | : | 0 |
| Group A |
May 28 • 00:00 | SE Palmeiras | | - | | Universitario de Deportes | 6 | : | 0 |
| Group A |
May 28 • 00:00 | Defensa y Justicia | | - | | Independiente del Valle | 1 | : | 1 |
| Group G |
May 28 • 02:00 | Flamengo | | - | | Vélez Sársfield | 0 | : | 0 |
| Group G |
May 28 • 02:00 | LDU Quito | | - | | Unión La Calera | 5 | : | 2 |
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| Jul 14 • 00:15 | Boca Juniors | | - | | Atlético Mineiro | 0 | : | 0 |
| Jul 14 • 00:15 | Cerro Porteño | | - | | Fluminense FC | 0 | : | 2 |
| Jul 14 • 02:30 | São Paulo FC | | - | | Racing Club | 1 | : | 1 |
| Jul 15 • 00:15 | CD Universidad Católica | | - | | SE Palmeiras | 0 | : | 1 |
| Jul 15 • 00:15 | Vélez Sársfield | | - | | Barcelona SC | 1 | : | 0 |
| Jul 15 • 02:30 | River Plate | | - | | Argentinos Juniors | 1 | : | 1 |
| Jul 15 • 02:30 | Defensa y Justicia | | - | | Flamengo | 0 | : | 1 |
| Jul 16 • 02:30 | Olimpia Asunción | | - | | SC Internacional | 0 | : | 0 |
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| Jul 21 • 00:15 | Atlético Mineiro | | - | | Boca Juniors | 0 | : | 0 |
| Jul 21 • 02:30 | Racing Club | | - | | São Paulo FC | 1 | : | 3 |
| Jul 22 • 00:15 | SE Palmeiras | | - | | CD Universidad Católica | 1 | : | 0 |
| Jul 22 • 00:15 | Barcelona SC | | - | | Vélez Sársfield | 3 | : | 1 |
| Jul 22 • 02:30 | Argentinos Juniors | | - | | River Plate | 0 | : | 2 |
| Jul 22 • 02:30 | Flamengo | | - | | Defensa y Justicia | 4 | : | 1 |
| Jul 23 • 02:30 | SC Internacional | | - | | Olimpia Asunción | 0 | : | 0 |
| Aug 04 • 00:15 | Fluminense FC | | - | | Cerro Porteño | 1 | : | 0 |
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| Aug 11 • 02:30 | São Paulo FC | | - | | SE Palmeiras | 1 | : | 1 |
| Aug 12 • 00:15 | Olimpia Asunción | | - | | Flamengo | 1 | : | 4 |
| Aug 12 • 02:30 | River Plate | | - | | Atlético Mineiro | 0 | : | 1 |
| Aug 13 • 02:30 | Fluminense FC | | - | | Barcelona SC | 2 | : | 2 |
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| Aug 18 • 02:30 | SE Palmeiras | | - | | São Paulo FC | 3 | : | 0 |
| Aug 19 • 00:15 | Flamengo | | - | | Olimpia Asunción | 5 | : | 1 |
| Aug 19 • 02:30 | Atlético Mineiro | | - | | River Plate | 3 | : | 0 |
| Aug 20 • 02:30 | Barcelona SC | | - | | Fluminense FC | 1 | : | 1 |
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| Sep 22 • 02:30 | SE Palmeiras | | - | | Atlético Mineiro | 0 | : | 0 |
| Sep 23 • 02:30 | Flamengo | | - | | Barcelona SC | 2 | : | 0 |
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| Sep 29 • 02:30 | Atlético Mineiro | | - | | SE Palmeiras | 1 | : | 1 |
| Sep 30 • 02:30 | Barcelona SC | | - | | Flamengo | 0 | : | 2 |
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| Nov 27 • 21:00 | SE Palmeiras | | - | | Flamengo | 2 | : | 1 |
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