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| Race | Winner | |||
| 1 |  Grand Prix of Qatar Losail International Circuit |
March 28 |  Maverick Viñales Yamaha | |
| 2 | Grand Prix of Doha Losail International Circuit |
April 04 |  Fabio Quartararo Yamaha | |
| 3 |  Portuguese Grand Prix Algarve International Circuit |
April 18 | Fabio Quartararo Yamaha | |
| 4 | Spanish Grand Prix Circuito de Jerez |
May 02 |  Jack Miller Ducati | |
| 5 | French Grand Prix Circuit Bugatti |
May 16 | Jack Miller Ducati | |
| 6 |  Italian Grand Prix Mugello Circuit |
May 30 | Fabio Quartararo Yamaha | |
| 7 | Catalan Grand Prix Circuit de Barcelona-Catalunya |
June 06 | Miguel Oliveira KTM | |
| 8 |  German Grand Prix Sachsenring |
June 20 | Marc Márquez Honda | |
| 9 |  Dutch TT Circuit Assen |
June 27 | Fabio Quartararo Yamaha | |
| 10 |  Styrian Grand Prix Red Bull Ring |
August 08 | Jorge Martín Ducati | |
| 11 | Austrian Grand Prix Red Bull Ring |
August 15 |  Brad Binder KTM | |
| 12 |  British Grand Prix Silverstone Circuit |
August 29 | Fabio Quartararo Yamaha | |
| 13 | Aragon Grand Prix MotorLand Aragón |
September 12 | Francesco Bagnaia Ducati | |
| 14 |  San Marino Grand Prix Misano World Circuit |
September 19 | Francesco Bagnaia Ducati | |
| 15 |  Grand Prix of the Americas Circuit of the Americas |
October 03 | Marc Márquez Honda | |
| 16 | Emilia Romagna Grand Prix Misano World Circuit |
October 24 | Marc Márquez Honda | |
| 17 | Algarve Grand Prix Algarve International Circuit |
November 07 | Francesco Bagnaia Ducati | |
| 18 | Valencian Community Grand Prix Circuit Ricardo Tormo |
November 14 | Francesco Bagnaia Ducati | |
| Season: | ||||
