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| Jan 29 • 22:30 | Arsenal de Sarandí |  | - |  | Mineros de Guayana | 2 | : | 0 |
| Jan 31 • 00:50 | Cruzeiro EC |  | - |  | Cerro Porteño | 3 | : | 1 |
| Jan 31 • 03:10 | CF Atlas |  | - |  | La Paz FC | 2 | : | 0 |
| Jan 31 • 23:00 | CD Olmedo |  | - |  | CA Lanús | 1 | : | 0 |
| Feb 01 • 01:20 | Cienciano del Cuzco |  | - |  | Montevideo Wanderers | 1 | : | 0 |
| Feb 08 • 01:00 | Boyacá Chicó |  | - |  | Audax Italiano | 4 | : | 3 |
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| Feb 05 • 23:00 | CA Lanús | | - | | CD Olmedo | 3 | : | 0 |
| Feb 06 • 01:30 | Mineros de Guayana | | - | | Arsenal de Sarandí | 2 | : | 1 |
| Feb 06 • 22:20 | La Paz FC | | - | | CF Atlas | 1 | : | 0 |
| Feb 07 • 00:50 | Cerro Porteño | | - | | Cruzeiro EC | 2 | : | 3 |
| Feb 07 • 22:30 | Montevideo Wanderers | | - | | Cienciano del Cuzco | 0 | : | 0 |
| Feb 12 • 21:00 | Audax Italiano | | - | | Boyacá Chicó | 1 | : | 0 |
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| Group A |
Feb 12 • 23:20 | Caracas FC |  | - |  | San Lorenzo | 2 | : | 0 |
| Group B |
Feb 13 • 01:40 | Deportivo Cuenca |  | - |  | Estudiantes de La Plata | 1 | : | 0 |
| Group E |
Feb 13 • 22:30 | Universidad San Martín |  | - |  | River Plate | 2 | : | 0 |
| Group A |
Feb 14 • 00:50 | Cruzeiro EC | | - |  | Real Potosí | 3 | : | 0 |
| Group D |
Feb 14 • 00:50 | Coronel Bolognesi |  | - |  | Flamengo | 0 | : | 0 |
| Group F |
Feb 14 • 03:10 | Cúcuta Deportivo |  | - |  | Santos FC | 0 | : | 0 |
| Group D |
Feb 14 • 22:30 | Cienciano del Cuzco | | - |  | Club Nacional Asunción | 2 | : | 1 |
| Group B |
Feb 15 • 00:50 | CA Lanús | | - |  | Danubio FC | 3 | : | 1 |
| Group G |
Feb 20 • 01:20 | Audax Italiano | | - |  | Sportivo Luqueño | 1 | : | 2 |
| Group F |
Feb 20 • 03:40 | Chivas Guadalajara |  | - |  | Club San José | 2 | : | 0 |
| Group H |
Feb 20 • 22:40 | Arsenal de Sarandí | | - |  | Club Libertad | 1 | : | 0 |
| Group C |
Feb 21 • 01:00 | UA Maracaibo |  | - |  | Boca Juniors | 1 | : | 1 |
| Group H |
Feb 21 • 01:50 | LDU Quito |  | - |  | Fluminense FC | 0 | : | 0 |
| Group E |
Feb 21 • 04:10 | Club América |  | - |  | CD Universidad Católica | 2 | : | 1 |
| Group C |
Feb 22 • 03:40 | CF Atlas | | - |  | Colo-Colo | 3 | : | 0 |
| Group G |
Feb 28 • 01:50 | Atlético Nacional |  | - |  | São Paulo FC | 1 | : | 1 |
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| Group D |
Feb 19 • 23:00 | Coronel Bolognesi | | - | | Club Nacional Asunción | 0 | : | 1 |
| Group A |
Feb 21 • 23:00 | San Lorenzo | | - | | Cruzeiro EC | 0 | : | 0 |
| Group B |
Feb 22 • 01:20 | Deportivo Cuenca | | - | | Danubio FC | 0 | : | 0 |
| Group B |
Feb 26 • 22:00 | Estudiantes de La Plata | | - | | CA Lanús | 0 | : | 0 |
| Group A |
Feb 27 • 00:20 | Caracas FC | | - | | Real Potosí | 2 | : | 1 |
| Group E |
Feb 27 • 02:40 | Universidad San Martín | | - | | CD Universidad Católica | 0 | : | 1 |
| Group E |
Feb 27 • 23:30 | River Plate | | - | | Club América | 2 | : | 1 |
| Group D |
Feb 28 • 01:50 | Flamengo | | - | | Cienciano del Cuzco | 2 | : | 1 |
| Group C |
Feb 29 • 01:20 | UA Maracaibo | | - | | Colo-Colo | 1 | : | 3 |
| Group F |
Feb 29 • 03:40 | Cúcuta Deportivo | | - | | Club San José | 0 | : | 0 |
| Group H |
Mar 04 • 21:00 | LDU Quito | | - | | Club Libertad | 2 | : | 0 |
| Group F |
Mar 05 • 01:50 | Santos FC | | - | | Chivas Guadalajara | 1 | : | 0 |
| Group G |
Mar 06 • 01:50 | São Paulo FC | | - | | Audax Italiano | 2 | : | 1 |
| Group H |
Mar 06 • 01:50 | Fluminense FC | | - | | Arsenal de Sarandí | 6 | : | 0 |
| Group C |
Mar 07 • 00:20 | Boca Juniors | | - | | CF Atlas | 3 | : | 0 |
| Group G |
Mar 07 • 03:00 | Atlético Nacional | | - | | Sportivo Luqueño | 3 | : | 0 |
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| Group A |
Mar 04 • 23:20 | Cruzeiro EC | | - | | Caracas FC | 3 | : | 0 |
| Group B |
Mar 05 • 23:30 | Danubio FC | | - | | Estudiantes de La Plata | 1 | : | 2 |
| Group D |
Mar 06 • 22:00 | Club Nacional Asunción | | - | | Flamengo | 3 | : | 0 |
| Group D |
Mar 11 • 22:50 | Cienciano del Cuzco | | - | | Coronel Bolognesi | 1 | : | 0 |
| Group A |
Mar 12 • 01:10 | Real Potosí | | - | | San Lorenzo | 2 | : | 3 |
| Group F |
Mar 12 • 03:30 | Chivas Guadalajara | | - | | Cúcuta Deportivo | 0 | : | 1 |
| Group H |
Mar 12 • 22:10 | Arsenal de Sarandí | | - | | LDU Quito | 0 | : | 1 |
| Group E |
Mar 13 • 01:10 | CD Universidad Católica | | - | | River Plate | 1 | : | 2 |
| Group C |
Mar 13 • 03:40 | CF Atlas | | - | | UA Maracaibo | 3 | : | 0 |
| Group B |
Mar 14 • 00:10 | CA Lanús | | - | | Deportivo Cuenca | 0 | : | 0 |
| Group E |
Mar 14 • 02:30 | Club América | | - | | Universidad San Martín | 3 | : | 1 |
| Group G |
Mar 19 • 01:50 | Audax Italiano | | - | | Atlético Nacional | 1 | : | 0 |
| Group H |
Mar 19 • 23:30 | Club Libertad | | - | | Fluminense FC | 1 | : | 2 |
| Group F |
Mar 20 • 01:50 | Club San José | | - | | Santos FC | 2 | : | 1 |
| Group G |
Mar 20 • 23:20 | Sportivo Luqueño | | - | | São Paulo FC | 1 | : | 1 |
| Group C |
Mar 21 • 01:40 | Colo-Colo | | - | | Boca Juniors | 2 | : | 0 |
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| Group B |
Mar 18 • 23:30 | Estudiantes de La Plata | | - | | Danubio FC | 2 | : | 0 |
| Group A |
Mar 19 • 01:50 | Caracas FC | | - | | Cruzeiro EC | 1 | : | 1 |
| Group D |
Mar 20 • 01:50 | Flamengo | | - | | Club Nacional Asunción | 2 | : | 0 |
| Group B |
Mar 20 • 21:00 | Deportivo Cuenca | | - | | CA Lanús | 1 | : | 1 |
| Group A |
Mar 25 • 23:00 | San Lorenzo | | - | | Real Potosí | 1 | : | 0 |
| Group C |
Mar 26 • 01:20 | UA Maracaibo | | - | | CF Atlas | 1 | : | 1 |
| Group D |
Mar 26 • 03:40 | Coronel Bolognesi | | - | | Cienciano del Cuzco | 0 | : | 0 |
| Group H |
Mar 26 • 23:00 | LDU Quito | | - | | Arsenal de Sarandí | 6 | : | 1 |
| Group E |
Mar 27 • 01:20 | River Plate | | - | | CD Universidad Católica | 2 | : | 0 |
| Group E |
Mar 27 • 03:40 | Universidad San Martín | | - | | Club América | 1 | : | 0 |
| Group C |
Mar 28 • 01:00 | Boca Juniors | | - | | Colo-Colo | 4 | : | 3 |
| Group F |
Mar 28 • 03:30 | Cúcuta Deportivo | | - | | Chivas Guadalajara | 1 | : | 0 |
| Group F |
Apr 02 • 01:30 | Santos FC | | - | | Club San José | 7 | : | 0 |
| Group G |
Apr 03 • 02:50 | São Paulo FC | | - | | Sportivo Luqueño | 1 | : | 0 |
| Group H |
Apr 03 • 02:50 | Fluminense FC | | - | | Club Libertad | 2 | : | 0 |
| Group G |
Apr 04 • 04:20 | Atlético Nacional | | - | | Audax Italiano | 1 | : | 1 |
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| Group B |
Mar 27 • 22:30 | Danubio FC | | - | | Deportivo Cuenca | 2 | : | 0 |
| Group A |
Apr 01 • 23:10 | Real Potosí | | - | | Caracas FC | 3 | : | 1 |
| Group E |
Apr 02 • 03:50 | CD Universidad Católica | | - | | Universidad San Martín | 1 | : | 0 |
| Group B |
Apr 03 • 00:30 | CA Lanús | | - | | Estudiantes de La Plata | 3 | : | 3 |
| Group E |
Apr 03 • 05:10 | Club América | | - | | River Plate | 4 | : | 3 |
| Group D |
Apr 03 • 23:40 | Club Nacional Asunción | | - | | Coronel Bolognesi | 1 | : | 0 |
| Group A |
Apr 04 • 02:00 | Cruzeiro EC | | - | | San Lorenzo | 3 | : | 1 |
| Group F |
Apr 08 • 23:00 | Club San José | | - | | Cúcuta Deportivo | 2 | : | 4 |
| Group C |
Apr 09 • 01:30 | CF Atlas | | - | | Boca Juniors | 3 | : | 1 |
| Group H |
Apr 09 • 03:50 | Club Libertad | | - | | LDU Quito | 3 | : | 1 |
| Group H |
Apr 10 • 00:30 | Arsenal de Sarandí | | - | | Fluminense FC | 2 | : | 0 |
| Group D |
Apr 10 • 02:50 | Cienciano del Cuzco | | - | | Flamengo | 0 | : | 3 |
| Group F |
Apr 10 • 02:50 | Chivas Guadalajara | | - | | Santos FC | 3 | : | 2 |
| Group C |
Apr 11 • 01:10 | Colo-Colo | | - | | UA Maracaibo | 2 | : | 0 |
| Group G |
Apr 11 • 03:30 | Sportivo Luqueño | | - | | Atlético Nacional | 1 | : | 3 |
| Group G |
Apr 11 • 03:30 | Audax Italiano | | - | | São Paulo FC | 1 | : | 0 |
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| Group B |
Apr 16 • 02:10 | Danubio FC | | - | | CA Lanús | 1 | : | 2 |
| Group B |
Apr 16 • 02:10 | Estudiantes de La Plata | | - | | Deportivo Cuenca | 2 | : | 0 |
| Group A |
Apr 17 • 00:30 | Real Potosí | | - | | Cruzeiro EC | 5 | : | 1 |
| Group A |
Apr 17 • 00:30 | San Lorenzo | | - | | Caracas FC | 3 | : | 0 |
| Group F |
Apr 17 • 02:50 | Club San José | | - | | Chivas Guadalajara | 0 | : | 3 |
| Group F |
Apr 17 • 02:50 | Santos FC | | - | | Cúcuta Deportivo | 2 | : | 1 |
| Group H |
Apr 17 • 02:50 | Club Libertad | | - | | Arsenal de Sarandí | 1 | : | 2 |
| Group H |
Apr 18 • 00:10 | Fluminense FC | | - | | LDU Quito | 1 | : | 0 |
| Group E |
Apr 18 • 02:30 | River Plate | | - | | Universidad San Martín | 5 | : | 0 |
| Group E |
Apr 18 • 02:30 | CD Universidad Católica | | - | | Club América | 2 | : | 0 |
| Group C |
Apr 23 • 02:10 | Colo-Colo | | - | | CF Atlas | 1 | : | 1 |
| Group C |
Apr 23 • 02:10 | Boca Juniors | | - | | UA Maracaibo | 3 | : | 0 |
| Group D |
Apr 24 • 00:30 | Flamengo | | - | | Coronel Bolognesi | 2 | : | 0 |
| Group D |
Apr 24 • 00:30 | Club Nacional Asunción | | - | | Cienciano del Cuzco | 3 | : | 1 |
| Group G |
Apr 24 • 02:50 | Sportivo Luqueño | | - | | Audax Italiano | 4 | : | 1 |
| Group G |
Apr 24 • 02:50 | São Paulo FC | | - | | Atlético Nacional | 1 | : | 0 |
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| Apr 30 • 01:10 | CA Lanús | | - | | CF Atlas | 0 | : | 1 |
| Apr 30 • 03:30 | LDU Quito | | - | | Estudiantes de La Plata | 2 | : | 0 |
| Apr 30 • 22:40 | Boca Juniors | | - | | Cruzeiro EC | 2 | : | 1 |
| May 01 • 00:45 | Club América | | - | | Flamengo | 2 | : | 4 |
| May 01 • 00:45 | San Lorenzo | | - | | River Plate | 2 | : | 1 |
| May 01 • 03:00 | Atlético Nacional | | - | | Fluminense FC | 1 | : | 2 |
| May 01 • 03:00 | Club Nacional Asunción | | - | | São Paulo FC | 0 | : | 0 |
| May 02 • 01:45 | Santos FC | | - | | Cúcuta Deportivo | 2 | : | 0 |
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| May 06 • 23:30 | Fluminense FC | | - | | Atlético Nacional | 1 | : | 0 |
| May 07 • 02:00 | Estudiantes de La Plata | | - | | LDU Quito | 2 | : | 1 |
| May 07 • 04:30 | CF Atlas | | - | | CA Lanús | 2 | : | 2 |
| May 08 • 00:10 | Cruzeiro EC | | - | | Boca Juniors | 1 | : | 2 |
| May 08 • 02:50 | Flamengo | | - | | Club América | 0 | : | 3 |
| May 08 • 02:50 | São Paulo FC | | - | | Club Nacional Asunción | 2 | : | 0 |
| May 09 • 01:30 | River Plate | | - | | San Lorenzo | 2 | : | 2 |
| May 09 • 04:15 | Cúcuta Deportivo | | - | | Santos FC | 0 | : | 2 |
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| May 15 • 00:20 | Boca Juniors | | - | | CF Atlas | 2 | : | 2 |
| May 15 • 02:50 | São Paulo FC | | - | | Fluminense FC | 1 | : | 0 |
| May 16 • 00:00 | San Lorenzo | | - | | LDU Quito | 1 | : | 1 |
| May 16 • 02:20 | Club América | | - | | Santos FC | 2 | : | 0 |
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| May 22 • 00:20 | CF Atlas | | - | | Boca Juniors | 0 | : | 3 |
| May 22 • 02:50 | Fluminense FC | | - | | São Paulo FC | 3 | : | 1 |
| May 23 • 00:20 | LDU Quito | | - | | San Lorenzo | 6 | : | 4 |
| May 23 • 02:50 | Santos FC | | - | | Club América | 1 | : | 0 |
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| May 28 • 03:10 | Club América | | - | | LDU Quito | 1 | : | 1 |
| May 29 • 02:50 | Boca Juniors | | - | | Fluminense FC | 2 | : | 2 |
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| Jun 04 • 03:15 | LDU Quito | | - | | Club América | 0 | : | 0 |
| Jun 05 • 02:50 | Fluminense FC | | - | | Boca Juniors | 3 | : | 1 |
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| Jun 26 • 02:50 | LDU Quito | | - | | Fluminense FC | 4 | : | 2 |
| Jul 03 • 02:50 | Fluminense FC | | - | | LDU Quito | 4 | : | 4 |
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