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| Oct 16 • 20:45 | Harlequins |  | - |  | Wasps RFC | 26 | : | 21 |
| Oct 16 • 20:45 | Worcester Warriors |  | - |  | Northampton Saints | 13 | : | 12 |
| Oct 16 • 21:00 | Newcastle Falcons |  | - |  | Gloucester Rugby | 27 | : | 39 |
| Oct 17 • 15:00 | Bath Rugby |  | - |  | Exeter Chiefs | 19 | : | 17 |
| Oct 17 • 15:00 | Saracens |  | - |  | Sale Sharks | 41 | : | 3 |
| Oct 18 • 16:15 | London Irish |  | - |  | Leicester Tigers | 16 | : | 28 |
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| Oct 23 • 20:45 | Gloucester Rugby | | - | | Saracens | 15 | : | 17 |
| Oct 23 • 21:00 | Sale Sharks | | - | | Worcester Warriors | 27 | : | 13 |
| Oct 24 • 14:45 | Northampton Saints | | - | | Newcastle Falcons | 42 | : | 16 |
| Oct 24 • 15:00 | Wasps RFC | | - | | Bath Rugby | 16 | : | 9 |
| Oct 24 • 19:00 | Exeter Chiefs | | - | | London Irish | 38 | : | 11 |
| Oct 25 • 15:00 | Leicester Tigers | | - | | Harlequins | 22 | : | 19 |
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| Oct 31 • 14:00 | Saracens | | - | | London Irish | 24 | : | 14 |
| Oct 31 • 14:30 | Bath Rugby | | - | | Harlequins | 28 | : | 38 |
| Oct 31 • 15:00 | Gloucester Rugby | | - | | Worcester Warriors | 24 | : | 22 |
| Nov 01 • 14:00 | Newcastle Falcons | | - | | Exeter Chiefs | 3 | : | 41 |
| Nov 01 • 15:30 | Sale Sharks | | - | | Northampton Saints | 20 | : | 13 |
| Nov 01 • 16:15 | Leicester Tigers | | - | | Wasps RFC | 24 | : | 16 |
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| Nov 06 • 20:45 | Harlequins | | - | | Sale Sharks | 16 | : | 14 |
| Nov 07 • 16:00 | London Irish | | - | | Bath Rugby | 14 | : | 45 |
| Nov 07 • 16:00 | Worcester Warriors | | - | | Newcastle Falcons | 28 | : | 20 |
| Nov 07 • 16:15 | Northampton Saints | | - | | Saracens | 6 | : | 12 |
| Nov 07 • 18:30 | Exeter Chiefs | | - | | Leicester Tigers | 19 | : | 6 |
| Nov 08 • 16:00 | Wasps RFC | | - | | Gloucester Rugby | 23 | : | 3 |
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| Nov 27 • 20:45 | Northampton Saints | | - | | Gloucester Rugby | 15 | : | 3 |
| Nov 28 • 15:30 | Sale Sharks | | - | | Newcastle Falcons | 15 | : | 15 |
| Nov 28 • 16:00 | Exeter Chiefs | | - | | Harlequins | 26 | : | 25 |
| Nov 28 • 16:15 | Saracens | | - | | Worcester Warriors | 48 | : | 18 |
| Nov 28 • 18:30 | London Irish | | - | | Wasps RFC | 15 | : | 33 |
| Nov 29 • 16:00 | Leicester Tigers | | - | | Bath Rugby | 21 | : | 11 |
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| Dec 04 • 20:45 | Gloucester Rugby | | - | | Sale Sharks | 23 | : | 19 |
| Dec 05 • 16:00 | Harlequins | | - | | London Irish | 38 | : | 7 |
| Dec 05 • 16:00 | Worcester Warriors | | - | | Leicester Tigers | 20 | : | 29 |
| Dec 05 • 16:15 | Bath Rugby | | - | | Northampton Saints | 11 | : | 13 |
| Dec 05 • 18:30 | Wasps RFC | | - | | Exeter Chiefs | 27 | : | 41 |
| Dec 06 • 16:00 | Newcastle Falcons | | - | | Saracens | 3 | : | 38 |
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| Dec 26 • 15:30 | London Irish | | - | | Northampton Saints | 25 | : | 23 |
| Dec 26 • 16:00 | Exeter Chiefs | | - | | Sale Sharks | 33 | : | 17 |
| Dec 26 • 16:00 | Leicester Tigers | | - | | Newcastle Falcons | 22 | : | 10 |
| Dec 27 • 15:00 | Wasps RFC | | - | | Saracens | 16 | : | 26 |
| Dec 27 • 15:30 | Bath Rugby | | - | | Worcester Warriors | 21 | : | 14 |
| Dec 27 • 17:30 | Harlequins | | - | | Gloucester Rugby | 39 | : | 39 |
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| Jan 01 • 16:00 | Northampton Saints | | - | | Exeter Chiefs | 8 | : | 3 |
| Jan 02 • 16:00 | Gloucester Rugby | | - | | London Irish | 27 | : | 14 |
| Jan 02 • 16:00 | Newcastle Falcons | | - | | Bath Rugby | 19 | : | 14 |
| Jan 02 • 16:15 | Saracens | | - | | Leicester Tigers | 26 | : | 6 |
| Jan 02 • 18:30 | Sale Sharks | | - | | Wasps RFC | 15 | : | 9 |
| Jan 03 • 16:00 | Worcester Warriors | | - | | Harlequins | 20 | : | 24 |
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| Jan 09 • 16:00 | Exeter Chiefs | | - | | Gloucester Rugby | 19 | : | 10 |
| Jan 09 • 16:00 | Harlequins | | - | | Saracens | 29 | : | 23 |
| Jan 09 • 16:15 | Leicester Tigers | | - | | Northampton Saints | 30 | : | 27 |
| Jan 10 • 14:00 | London Irish | | - | | Newcastle Falcons | 20 | : | 15 |
| Jan 10 • 15:00 | Wasps RFC | | - | | Worcester Warriors | 32 | : | 22 |
| Apr 23 • 16:15 | Bath Rugby | | - | | Sale Sharks | 32 | : | 26 |
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| Jan 29 • 20:45 | Northampton Saints | | - | | Wasps RFC | 11 | : | 24 |
| Jan 30 • 15:30 | Sale Sharks | | - | | London Irish | 38 | : | 10 |
| Jan 30 • 16:00 | Gloucester Rugby | | - | | Leicester Tigers | 18 | : | 19 |
| Jan 30 • 16:15 | Saracens | | - | | Bath Rugby | 19 | : | 13 |
| Jan 31 • 16:00 | Worcester Warriors | | - | | Exeter Chiefs | 15 | : | 30 |
| Jan 31 • 16:00 | Newcastle Falcons | | - | | Harlequins | 26 | : | 19 |
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| Feb 05 • 20:45 | Bath Rugby | | - | | Gloucester Rugby | 11 | : | 15 |
| Feb 06 • 15:00 | Wasps RFC | | - | | Newcastle Falcons | 9 | : | 8 |
| Feb 06 • 15:00 | Harlequins | | - | | Northampton Saints | 23 | : | 27 |
| Feb 06 • 16:00 | Leicester Tigers | | - | | Sale Sharks | 3 | : | 10 |
| Feb 07 • 14:00 | Exeter Chiefs | | - | | Saracens | 11 | : | 14 |
| Feb 07 • 14:00 | London Irish | | - | | Worcester Warriors | 20 | : | 13 |
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| Feb 12 • 20:45 | Newcastle Falcons | | - | | Leicester Tigers | 26 | : | 14 |
| Feb 13 • 15:30 | Sale Sharks | | - | | Exeter Chiefs | 23 | : | 17 |
| Feb 13 • 16:00 | Gloucester Rugby | | - | | Harlequins | 28 | : | 6 |
| Feb 13 • 16:00 | Northampton Saints | | - | | London Irish | 35 | : | 7 |
| Feb 13 • 16:00 | Worcester Warriors | | - | | Bath Rugby | 14 | : | 16 |
| Feb 14 • 17:00 | Saracens | | - | | Wasps RFC | 23 | : | 64 |
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| Feb 19 • 20:45 | Harlequins | | - | | Leicester Tigers | 25 | : | 19 |
| Feb 20 • 16:00 | Saracens | | - | | Gloucester Rugby | 25 | : | 12 |
| Feb 20 • 16:00 | Worcester Warriors | | - | | Sale Sharks | 31 | : | 23 |
| Feb 20 • 16:15 | Bath Rugby | | - | | Wasps RFC | 18 | : | 24 |
| Feb 21 • 16:00 | London Irish | | - | | Exeter Chiefs | 15 | : | 22 |
| Feb 21 • 16:00 | Newcastle Falcons | | - | | Northampton Saints | 26 | : | 25 |
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| Feb 27 • 14:00 | Sale Sharks | | - | | Saracens | 36 | : | 36 |
| Feb 27 • 15:45 | Northampton Saints | | - | | Worcester Warriors | 38 | : | 18 |
| Feb 27 • 16:00 | Gloucester Rugby | | - | | Newcastle Falcons | 32 | : | 6 |
| Feb 28 • 14:00 | Exeter Chiefs | | - | | Bath Rugby | 26 | : | 17 |
| Feb 28 • 16:00 | Leicester Tigers | | - | | London Irish | 47 | : | 20 |
| Feb 28 • 16:15 | Wasps RFC | | - | | Harlequins | 42 | : | 10 |
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| Mar 04 • 20:45 | Newcastle Falcons | | - | | Worcester Warriors | 14 | : | 15 |
| Mar 05 • 15:30 | Sale Sharks | | - | | Harlequins | 29 | : | 23 |
| Mar 05 • 16:00 | Gloucester Rugby | | - | | Wasps RFC | 13 | : | 10 |
| Mar 05 • 16:15 | Saracens | | - | | Northampton Saints | 15 | : | 20 |
| Mar 05 • 16:15 | Bath Rugby | | - | | London Irish | 25 | : | 17 |
| Mar 06 • 16:00 | Leicester Tigers | | - | | Exeter Chiefs | 31 | : | 27 |
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| Mar 11 • 20:45 | Harlequins | | - | | Bath Rugby | 35 | : | 28 |
| Mar 12 • 14:45 | Wasps RFC | | - | | Leicester Tigers | 36 | : | 17 |
| Mar 12 • 15:00 | Northampton Saints | | - | | Sale Sharks | 26 | : | 11 |
| Mar 12 • 15:00 | Worcester Warriors | | - | | Gloucester Rugby | 28 | : | 20 |
| Mar 12 • 16:00 | Exeter Chiefs | | - | | Newcastle Falcons | 32 | : | 17 |
| Mar 12 • 21:00 | London Irish | | - | | Saracens | 16 | : | 26 |
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| Mar 18 • 20:45 | Bath Rugby | | - | | Newcastle Falcons | 21 | : | 19 |
| Mar 19 • 16:00 | Harlequins | | - | | Worcester Warriors | 15 | : | 21 |
| Mar 20 • 14:00 | Exeter Chiefs | | - | | Northampton Saints | 20 | : | 12 |
| Mar 20 • 15:00 | Wasps RFC | | - | | Sale Sharks | 39 | : | 12 |
| Mar 20 • 16:00 | London Irish | | - | | Gloucester Rugby | 23 | : | 18 |
| Mar 20 • 16:15 | Leicester Tigers | | - | | Saracens | 21 | : | 13 |
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| Mar 26 • 16:15 | Saracens | | - | | Exeter Chiefs | 36 | : | 18 |
| Mar 26 • 18:30 | Gloucester Rugby | | - | | Bath Rugby | 12 | : | 17 |
| Mar 26 • 18:30 | Worcester Warriors | | - | | London Irish | 12 | : | 6 |
| Mar 27 • 14:00 | Sale Sharks | | - | | Leicester Tigers | 27 | : | 20 |
| Mar 27 • 16:00 | Newcastle Falcons | | - | | Wasps RFC | 20 | : | 34 |
| Mar 27 • 16:15 | Northampton Saints | | - | | Harlequins | 29 | : | 23 |
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| Apr 01 • 20:45 | Bath Rugby | | - | | Saracens | 10 | : | 30 |
| Apr 02 • 16:00 | Exeter Chiefs | | - | | Worcester Warriors | 50 | : | 12 |
| Apr 02 • 16:00 | Harlequins | | - | | Newcastle Falcons | 46 | : | 25 |
| Apr 02 • 16:00 | London Irish | | - | | Sale Sharks | 15 | : | 30 |
| Apr 02 • 16:15 | Leicester Tigers | | - | | Gloucester Rugby | 35 | : | 30 |
| Apr 03 • 16:00 | Wasps RFC | | - | | Northampton Saints | 28 | : | 6 |
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| Apr 15 • 20:45 | Gloucester Rugby | | - | | Exeter Chiefs | 16 | : | 9 |
| Apr 16 • 16:00 | Worcester Warriors | | - | | Wasps RFC | 35 | : | 54 |
| Apr 16 • 16:15 | Saracens | | - | | Harlequins | 22 | : | 12 |
| Apr 16 • 18:30 | Northampton Saints | | - | | Leicester Tigers | 24 | : | 30 |
| Apr 17 • 15:30 | Sale Sharks | | - | | Bath Rugby | 29 | : | 17 |
| Apr 17 • 16:00 | Newcastle Falcons | | - | | London Irish | 13 | : | 6 |
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| Apr 29 • 20:45 | Sale Sharks | | - | | Gloucester Rugby | 11 | : | 12 |
| Apr 30 • 16:00 | Leicester Tigers | | - | | Worcester Warriors | 31 | : | 17 |
| Apr 30 • 16:15 | Northampton Saints | | - | | Bath Rugby | 15 | : | 14 |
| May 01 • 14:00 | Exeter Chiefs | | - | | Wasps RFC | 24 | : | 3 |
| May 01 • 16:00 | London Irish | | - | | Harlequins | 25 | : | 32 |
| May 01 • 16:15 | Saracens | | - | | Newcastle Falcons | 23 | : | 14 |
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| May 07 • 16:30 | Bath Rugby | | - | | Leicester Tigers | 38 | : | 27 |
| May 07 • 16:30 | Gloucester Rugby | | - | | Northampton Saints | 20 | : | 28 |
| May 07 • 16:30 | Harlequins | | - | | Exeter Chiefs | 24 | : | 62 |
| May 07 • 16:30 | Newcastle Falcons | | - | | Sale Sharks | 15 | : | 21 |
| May 07 • 16:30 | Wasps RFC | | - | | London Irish | 38 | : | 12 |
| May 07 • 16:30 | Worcester Warriors | | - | | Saracens | 19 | : | 43 |
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| May 21 • 13:30 | Saracens | | - | | Leicester Tigers | 44 | : | 17 |
| May 21 • 16:15 | Exeter Chiefs | | - | | Wasps RFC | 34 | : | 23 |
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| May 28 • 16:00 | Saracens | | - | | Exeter Chiefs | 28 | : | 20 |
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