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| Feb 20 • 23:00 | Portuguesa FC |  | - |  | CD Palestino | 1 | : | 2 |
| Feb 21 • 01:30 | Águilas Doradas |  | - |  | RB Bragantino | 0 | : | 0 |
| Feb 21 • 01:30 | Club Always Ready |  | - |  | Sporting Cristal | 6 | : | 1 |
| Feb 21 • 23:00 | Academia Puerto Cabello |  | - |  | Club Nacional Montevideo | 0 | : | 2 |
| Feb 22 • 01:30 | Club Nacional Asunción |  | - |  | Atlético Nacional | 1 | : | 0 |
| Feb 22 • 01:30 | Club Aurora |  | - |  | Botafogo | 1 | : | 1 |
| Feb 22 • 23:00 | Sportivo Trinidense |  | - |  | El Nacional | 1 | : | 1 |
| Feb 23 • 01:30 | Godoy Cruz |  | - |  | Colo-Colo | 0 | : | 1 |
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| Feb 27 • 23:00 | CD Palestino | | - | | Portuguesa FC | 2 | : | 1 |
| Feb 28 • 01:30 | RB Bragantino | | - | | Águilas Doradas | 0 | : | 0 |
| Feb 28 • 01:30 | Sporting Cristal | | - | | Club Always Ready | 3 | : | 1 |
| Feb 28 • 23:00 | Club Nacional Montevideo | | - | | Academia Puerto Cabello | 2 | : | 0 |
| Feb 29 • 01:30 | Atlético Nacional | | - | | Club Nacional Asunción | 0 | : | 3 |
| Feb 29 • 01:30 | Botafogo | | - | | Club Aurora | 6 | : | 0 |
| Feb 29 • 23:00 | El Nacional | | - | | Sportivo Trinidense | 0 | : | 1 |
| Mar 01 • 01:30 | Colo-Colo | | - | | Godoy Cruz | 0 | : | 0 |
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| Mar 06 • 01:30 | Club Nacional Asunción | | - | | CD Palestino | 0 | : | 2 |
| Mar 07 • 01:30 | Botafogo | | - | | RB Bragantino | 2 | : | 1 |
| Mar 07 • 01:30 | Sportivo Trinidense | | - | | Colo-Colo | 1 | : | 1 |
| Mar 08 • 01:30 | Club Always Ready | | - | | Club Nacional Montevideo | 1 | : | 0 |
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| Mar 13 • 01:30 | CD Palestino | | - | | Club Nacional Asunción | 1 | : | 3 |
| Mar 14 • 01:30 | RB Bragantino | | - | | Botafogo | 1 | : | 1 |
| Mar 14 • 01:30 | Colo-Colo | | - | | Sportivo Trinidense | 2 | : | 1 |
| Mar 15 • 01:30 | Club Nacional Montevideo | | - | | Club Always Ready | 2 | : | 1 |
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| Group B |
Apr 03 • 00:00 | CD Cobresal |  | - |  | Barcelona SC | 1 | : | 1 |
| Group E |
Apr 03 • 00:00 | Los Millonarios |  | - |  | Flamengo | 1 | : | 1 |
| Group C |
Apr 03 • 02:00 | The Strongest |  | - |  | Grêmio Porto Alegrense | 2 | : | 0 |
| Group H |
Apr 03 • 02:00 | Deportivo Táchira |  | - |  | River Plate | 0 | : | 2 |
| Group D |
Apr 03 • 04:00 | Universitario de Deportes |  | - |  | LDU Quito | 2 | : | 1 |
| Group C |
Apr 04 • 00:00 | CD Huachipato |  | - |  | Estudiantes de La Plata | 1 | : | 1 |
| Group D |
Apr 04 • 00:00 | Botafogo | | - |  | Atlético Junior | 1 | : | 3 |
| Group H |
Apr 04 • 00:00 | Club Nacional Montevideo | | - |  | Club Libertad | 2 | : | 0 |
| Group A |
Apr 04 • 02:00 | Colo-Colo | | - |  | Cerro Porteño | 1 | : | 0 |
| Group A |
Apr 04 • 02:30 | Alianza Lima |  | - |  | Fluminense FC | 1 | : | 1 |
| Group F |
Apr 04 • 02:30 | San Lorenzo |  | - |  | SE Palmeiras | 1 | : | 1 |
| Group G |
Apr 05 • 00:00 | Rosario Central |  | - |  | CA Peñarol | 1 | : | 0 |
| Group G |
Apr 05 • 00:00 | Caracas FC |  | - |  | Atlético Mineiro | 1 | : | 4 |
| Group B |
Apr 05 • 02:00 | Talleres de Córdoba |  | - |  | São Paulo FC | 2 | : | 1 |
| Group E |
Apr 05 • 02:00 | CD Palestino | | - |  | Club Bolívar | 0 | : | 4 |
| Group F |
Apr 05 • 02:00 | Liverpool FC |  | - |  | Independiente del Valle | 1 | : | 1 |
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| Group C |
Apr 10 • 00:00 | Estudiantes de La Plata | | - | | The Strongest | 2 | : | 1 |
| Group C |
Apr 10 • 00:00 | Grêmio Porto Alegrense | | - | | CD Huachipato | 0 | : | 2 |
| Group A |
Apr 10 • 02:00 | Fluminense FC | | - | | Colo-Colo | 2 | : | 1 |
| Group H |
Apr 10 • 02:00 | Club Libertad | | - | | Deportivo Táchira | 3 | : | 0 |
| Group D |
Apr 10 • 04:00 | Atlético Junior | | - | | Universitario de Deportes | 1 | : | 1 |
| Group A |
Apr 11 • 00:00 | Cerro Porteño | | - | | Alianza Lima | 1 | : | 0 |
| Group F |
Apr 11 • 00:00 | Independiente del Valle | | - | | San Lorenzo | 2 | : | 0 |
| Group G |
Apr 11 • 00:00 | Atlético Mineiro | | - | | Rosario Central | 2 | : | 1 |
| Group G |
Apr 11 • 02:00 | CA Peñarol | | - | | Caracas FC | 5 | : | 0 |
| Group B |
Apr 11 • 02:30 | São Paulo FC | | - | | CD Cobresal | 2 | : | 0 |
| Group E |
Apr 11 • 02:30 | Flamengo | | - | | CD Palestino | 2 | : | 0 |
| Group B |
Apr 11 • 04:00 | Barcelona SC | | - | | Talleres de Córdoba | 2 | : | 2 |
| Group D |
Apr 12 • 00:00 | LDU Quito | | - | | Botafogo | 1 | : | 0 |
| Group E |
Apr 12 • 00:00 | Club Bolívar | | - | | Los Millonarios | 3 | : | 2 |
| Group F |
Apr 12 • 02:00 | SE Palmeiras | | - | | Liverpool FC | 3 | : | 1 |
| Group H |
Apr 12 • 02:00 | River Plate | | - | | Club Nacional Montevideo | 2 | : | 0 |
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| Group C |
Apr 24 • 00:00 | Estudiantes de La Plata | | - | | Grêmio Porto Alegrense | 0 | : | 1 |
| Group G |
Apr 24 • 00:00 | Caracas FC | | - | | Rosario Central | 1 | : | 1 |
| Group F |
Apr 24 • 02:00 | Liverpool FC | | - | | San Lorenzo | 1 | : | 0 |
| Group G |
Apr 24 • 02:00 | Atlético Mineiro | | - | | CA Peñarol | 3 | : | 2 |
| Group A |
Apr 24 • 02:30 | Colo-Colo | | - | | Alianza Lima | 0 | : | 0 |
| Group D |
Apr 24 • 04:00 | Atlético Junior | | - | | LDU Quito | 1 | : | 1 |
| Group C |
Apr 25 • 00:00 | CD Huachipato | | - | | The Strongest | 0 | : | 0 |
| Group D |
Apr 25 • 00:00 | Botafogo | | - | | Universitario de Deportes | 3 | : | 1 |
| Group H |
Apr 25 • 00:00 | Club Nacional Montevideo | | - | | Deportivo Táchira | 2 | : | 1 |
| Group E |
Apr 25 • 02:30 | Club Bolívar | | - | | Flamengo | 2 | : | 1 |
| Group F |
Apr 25 • 02:30 | Independiente del Valle | | - | | SE Palmeiras | 2 | : | 3 |
| Group H |
Apr 25 • 02:30 | Club Libertad | | - | | River Plate | 1 | : | 2 |
| Group A |
Apr 26 • 00:00 | Cerro Porteño | | - | | Fluminense FC | 0 | : | 0 |
| Group B |
Apr 26 • 00:00 | CD Cobresal | | - | | Talleres de Córdoba | 0 | : | 2 |
| Group B |
Apr 26 • 02:00 | Barcelona SC | | - | | São Paulo FC | 0 | : | 2 |
| Group E |
Apr 26 • 02:00 | CD Palestino | | - | | Los Millonarios | 3 | : | 1 |
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| Group G |
May 08 • 00:00 | Caracas FC | | - | | CA Peñarol | 0 | : | 1 |
| Group G |
May 08 • 00:00 | Rosario Central | | - | | Atlético Mineiro | 0 | : | 1 |
| Group E |
May 08 • 02:00 | CD Palestino | | - | | Flamengo | 1 | : | 0 |
| Group H |
May 08 • 02:00 | Deportivo Táchira | | - | | Club Libertad | 1 | : | 1 |
| Group H |
May 08 • 02:00 | Club Nacional Montevideo | | - | | River Plate | 2 | : | 2 |
| Group D |
May 08 • 04:00 | Universitario de Deportes | | - | | Atlético Junior | 1 | : | 1 |
| Group B |
May 09 • 00:00 | Talleres de Córdoba | | - | | Barcelona SC | 3 | : | 1 |
| Group A |
May 09 • 02:00 | Alianza Lima | | - | | Cerro Porteño | 1 | : | 1 |
| Group B |
May 09 • 02:30 | CD Cobresal | | - | | São Paulo FC | 1 | : | 3 |
| Group D |
May 09 • 02:30 | Botafogo | | - | | LDU Quito | 2 | : | 1 |
| Group E |
May 09 • 04:00 | Los Millonarios | | - | | Club Bolívar | 1 | : | 1 |
| Group F |
May 10 • 00:00 | Liverpool FC | | - | | SE Palmeiras | 0 | : | 5 |
| Group F |
May 10 • 00:00 | San Lorenzo | | - | | Independiente del Valle | 2 | : | 0 |
| Group A |
May 10 • 02:00 | Colo-Colo | | - | | Fluminense FC | 0 | : | 1 |
| Group C |
May 10 • 02:00 | The Strongest | | - | | Estudiantes de La Plata | 1 | : | 0 |
| Group C |
Jun 05 • 02:00 | CD Huachipato | | - | | Grêmio Porto Alegrense | 0 | : | 1 |
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| Group B |
May 15 • 00:00 | Talleres de Córdoba | | - | | CD Cobresal | 1 | : | 0 |
| Group D |
May 15 • 00:00 | LDU Quito | | - | | Atlético Junior | 0 | : | 1 |
| Group G |
May 15 • 00:00 | CA Peñarol | | - | | Atlético Mineiro | 2 | : | 0 |
| Group H |
May 15 • 02:30 | River Plate | | - | | Club Libertad | 2 | : | 0 |
| Group E |
May 15 • 04:00 | Los Millonarios | | - | | CD Palestino | 1 | : | 1 |
| Group C |
May 16 • 00:00 | The Strongest | | - | | CD Huachipato | 4 | : | 0 |
| Group H |
May 16 • 00:00 | Deportivo Táchira | | - | | Club Nacional Montevideo | 0 | : | 1 |
| Group A |
May 16 • 02:00 | Alianza Lima | | - | | Colo-Colo | 1 | : | 1 |
| Group E |
May 16 • 02:30 | Flamengo | | - | | Club Bolívar | 4 | : | 0 |
| Group F |
May 16 • 02:30 | SE Palmeiras | | - | | Independiente del Valle | 2 | : | 1 |
| Group A |
May 17 • 00:00 | Fluminense FC | | - | | Cerro Porteño | 2 | : | 1 |
| Group D |
May 17 • 00:00 | Universitario de Deportes | | - | | Botafogo | 0 | : | 1 |
| Group G |
May 17 • 00:00 | Rosario Central | | - | | Caracas FC | 4 | : | 1 |
| Group B |
May 17 • 02:00 | São Paulo FC | | - | | Barcelona SC | 0 | : | 0 |
| Group F |
May 17 • 02:00 | San Lorenzo | | - | | Liverpool FC | 3 | : | 2 |
| Group C |
Jun 09 • 00:00 | Grêmio Porto Alegrense | | - | | Estudiantes de La Plata | 1 | : | 1 |
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| Group D |
May 29 • 00:00 | Atlético Junior | | - | | Botafogo | 0 | : | 0 |
| Group D |
May 29 • 00:00 | LDU Quito | | - | | Universitario de Deportes | 2 | : | 0 |
| Group G |
May 29 • 00:00 | Atlético Mineiro | | - | | Caracas FC | 4 | : | 0 |
| Group G |
May 29 • 00:00 | CA Peñarol | | - | | Rosario Central | 2 | : | 1 |
| Group E |
May 29 • 02:00 | Club Bolívar | | - | | CD Palestino | 3 | : | 1 |
| Group E |
May 29 • 02:00 | Flamengo | | - | | Los Millonarios | 3 | : | 0 |
| Group C |
May 30 • 00:00 | Estudiantes de La Plata | | - | | CD Huachipato | 3 | : | 4 |
| Group C |
May 30 • 00:00 | Grêmio Porto Alegrense | | - | | The Strongest | 4 | : | 0 |
| Group A |
May 30 • 02:30 | Fluminense FC | | - | | Alianza Lima | 3 | : | 2 |
| Group A |
May 30 • 02:30 | Cerro Porteño | | - | | Colo-Colo | 1 | : | 1 |
| Group B |
May 30 • 02:30 | Barcelona SC | | - | | CD Cobresal | 2 | : | 1 |
| Group B |
May 30 • 02:30 | São Paulo FC | | - | | Talleres de Córdoba | 2 | : | 0 |
| Group F |
May 31 • 00:00 | Independiente del Valle | | - | | Liverpool FC | 2 | : | 1 |
| Group F |
May 31 • 00:00 | SE Palmeiras | | - | | San Lorenzo | 0 | : | 0 |
| Group H |
May 31 • 02:00 | Club Libertad | | - | | Club Nacional Montevideo | 2 | : | 1 |
| Group H |
May 31 • 02:00 | River Plate | | - | | Deportivo Táchira | 2 | : | 0 |
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| Aug 14 • 00:00 | Grêmio Porto Alegrense | | - | | Fluminense FC | 2 | : | 1 |
| Aug 14 • 02:30 | Colo-Colo | | - | | Atlético Junior | 1 | : | 0 |
| Aug 14 • 02:30 | San Lorenzo | | - | | Atlético Mineiro | 1 | : | 1 |
| Aug 15 • 00:00 | CA Peñarol | | - | | The Strongest | 4 | : | 0 |
| Aug 15 • 02:30 | Botafogo | | - | | SE Palmeiras | 2 | : | 1 |
| Aug 15 • 02:30 | Talleres de Córdoba | | - | | River Plate | 0 | : | 1 |
| Aug 16 • 00:00 | Club Nacional Montevideo | | - | | São Paulo FC | 0 | : | 0 |
| Aug 16 • 02:30 | Flamengo | | - | | Club Bolívar | 2 | : | 0 |
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| Aug 21 • 00:00 | Fluminense FC | | - | | Grêmio Porto Alegrense | 2 | : | 1 |
| Aug 21 • 02:30 | Atlético Mineiro | | - | | San Lorenzo | 1 | : | 0 |
| Aug 21 • 02:30 | Atlético Junior | | - | | Colo-Colo | 1 | : | 2 |
| Aug 22 • 00:00 | The Strongest | | - | | CA Peñarol | 1 | : | 0 |
| Aug 22 • 02:30 | SE Palmeiras | | - | | Botafogo | 2 | : | 2 |
| Aug 22 • 02:30 | River Plate | | - | | Talleres de Córdoba | 2 | : | 1 |
| Aug 23 • 00:00 | São Paulo FC | | - | | Club Nacional Montevideo | 2 | : | 0 |
| Aug 23 • 02:30 | Club Bolívar | | - | | Flamengo | 1 | : | 0 |
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| Sep 18 • 02:30 | Colo-Colo | | - | | River Plate | 1 | : | 1 |
| Sep 19 • 00:00 | Fluminense FC | | - | | Atlético Mineiro | 1 | : | 0 |
| Sep 19 • 02:30 | Botafogo | | - | | São Paulo FC | 0 | : | 0 |
| Sep 20 • 00:00 | Flamengo | | - | | CA Peñarol | 0 | : | 1 |
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| Sep 25 • 02:30 | River Plate | | - | | Colo-Colo | 1 | : | 0 |
| Sep 26 • 00:00 | Atlético Mineiro | | - | | Fluminense FC | 2 | : | 0 |
| Sep 26 • 02:30 | São Paulo FC | | - | | Botafogo | 1 | : | 1 |
| Sep 27 • 00:00 | CA Peñarol | | - | | Flamengo | 0 | : | 0 |
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| Oct 23 • 02:30 | Atlético Mineiro | | - | | River Plate | 3 | : | 0 |
| Oct 24 • 02:30 | Botafogo | | - | | CA Peñarol | 5 | : | 0 |
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| Oct 30 • 01:45 | River Plate | | - | | Atlético Mineiro | 0 | : | 0 |
| Oct 31 • 01:30 | CA Peñarol | | - | | Botafogo | 3 | : | 1 |
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| Nov 30 • 21:00 | Atlético Mineiro | | - | | Botafogo |
