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| Feb 14 • 01:30 | Santiago Wanderers |  | - |  | Independiente Santa Fe | 1 | : | 2 |
| Feb 14 • 23:00 | CA Banfield |  | - |  | Club Nacional Montevideo | 2 | : | 2 |
| Feb 15 • 00:45 | CR Vasco da Gama |  | - |  | Club Jorge Wilstermann | 4 | : | 0 |
| Feb 15 • 23:15 | Atlético Junior |  | - |  | Club Guaraní | 1 | : | 0 |
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| Feb 21 • 01:30 | Independiente Santa Fe | | - | | Santiago Wanderers | 3 | : | 0 |
| Feb 22 • 01:45 | Club Nacional Montevideo | | - | | CA Banfield | 1 | : | 0 |
| Feb 22 • 01:45 | Club Jorge Wilstermann | | - | | CR Vasco da Gama | 4 | : | 0 |
| Feb 23 • 01:30 | Club Guaraní | | - | | Atlético Junior | 0 | : | 0 |
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| Group A |
Feb 27 • 23:15 | Defensor Sporting |  | - |  | Grêmio Porto Alegrense | 1 | : | 1 |
| Group A |
Feb 27 • 23:15 | Monagas SC |  | - |  | Cerro Porteño | 0 | : | 2 |
| Group B |
Feb 28 • 01:30 | Colo-Colo |  | - |  | Atlético Nacional | 0 | : | 1 |
| Group E |
Feb 28 • 01:30 | Racing Club |  | - |  | Cruzeiro EC | 4 | : | 2 |
| Group F |
Feb 28 • 23:15 | Club Nacional Montevideo | | - |  | Estudiantes de La Plata | 0 | : | 0 |
| Group B |
Mar 01 • 01:45 | Delfín SC |  | - |  | Club Bolívar | 1 | : | 1 |
| Group D |
Mar 01 • 01:45 | Flamengo |  | - |  | River Plate | 2 | : | 2 |
| Group G |
Mar 01 • 01:45 | Los Millonarios |  | - |  | Corinthians | 0 | : | 0 |
| Group D |
Mar 01 • 23:15 | Independiente Santa Fe | | - |  | CS Emelec | 1 | : | 1 |
| Group F |
Mar 01 • 23:15 | Cusco FC |  | - |  | Santos FC | 2 | : | 0 |
| Group G |
Mar 01 • 23:15 | Deportivo Lara |  | - |  | Independiente | 1 | : | 0 |
| Group H |
Mar 02 • 01:30 | Alianza Lima |  | - |  | Boca Juniors | 0 | : | 0 |
| Group H |
Mar 02 • 01:30 | Atlético Junior | | - |  | SE Palmeiras | 0 | : | 3 |
| Group C |
Mar 13 • 23:15 | Atlético Tucumán |  | - |  | Club Libertad | 0 | : | 2 |
| Group E |
Mar 14 • 01:30 | CR Vasco da Gama | | - |  | Universidad de Chile | 0 | : | 1 |
| Group C |
Mar 15 • 23:15 | The Strongest |  | - |  | CA Peñarol | 1 | : | 0 |
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| Group A |
Mar 14 • 01:30 | Cerro Porteño | | - | | Defensor Sporting | 2 | : | 1 |
| Group B |
Mar 14 • 23:15 | Club Bolívar | | - | | Colo-Colo | 1 | : | 1 |
| Group F |
Mar 14 • 23:15 | Estudiantes de La Plata | | - | | Cusco FC | 3 | : | 0 |
| Group B |
Mar 15 • 01:45 | Atlético Nacional | | - | | Delfín SC | 4 | : | 0 |
| Group D |
Mar 15 • 01:45 | CS Emelec | | - | | Flamengo | 1 | : | 2 |
| Group G |
Mar 15 • 01:45 | Corinthians | | - | | Deportivo Lara | 2 | : | 0 |
| Group F |
Mar 15 • 23:15 | Santos FC | | - | | Club Nacional Montevideo | 3 | : | 1 |
| Group G |
Mar 16 • 01:30 | Independiente | | - | | Los Millonarios | 1 | : | 0 |
| Group C |
Apr 04 • 00:15 | Club Libertad | | - | | The Strongest | 3 | : | 0 |
| Group E |
Apr 04 • 02:30 | Universidad de Chile | | - | | Racing Club | 1 | : | 1 |
| Group H |
Apr 04 • 02:30 | SE Palmeiras | | - | | Alianza Lima | 2 | : | 0 |
| Group A |
Apr 05 • 00:15 | Grêmio Porto Alegrense | | - | | Monagas SC | 4 | : | 0 |
| Group C |
Apr 05 • 00:15 | CA Peñarol | | - | | Atlético Tucumán | 3 | : | 1 |
| Group E |
Apr 05 • 02:45 | Cruzeiro EC | | - | | CR Vasco da Gama | 0 | : | 0 |
| Group H |
Apr 05 • 02:45 | Boca Juniors | | - | | Atlético Junior | 1 | : | 0 |
| Group D |
Apr 06 • 00:15 | River Plate | | - | | Independiente Santa Fe | 0 | : | 0 |
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| Group F |
Apr 04 • 00:15 | Cusco FC | | - | | Club Nacional Montevideo | 0 | : | 0 |
| Group B |
Apr 06 • 00:15 | Colo-Colo | | - | | Delfín SC | 0 | : | 2 |
| Group B |
Apr 06 • 02:30 | Club Bolívar | | - | | Atlético Nacional | 1 | : | 0 |
| Group F |
Apr 06 • 02:30 | Estudiantes de La Plata | | - | | Santos FC | 0 | : | 1 |
| Group H |
Apr 12 • 02:45 | SE Palmeiras | | - | | Boca Juniors | 1 | : | 1 |
| Group A |
Apr 18 • 00:15 | Defensor Sporting | | - | | Monagas SC | 3 | : | 1 |
| Group A |
Apr 18 • 02:30 | Cerro Porteño | | - | | Grêmio Porto Alegrense | 0 | : | 0 |
| Group G |
Apr 18 • 02:30 | Los Millonarios | | - | | Deportivo Lara | 4 | : | 0 |
| Group C |
Apr 19 • 00:15 | The Strongest | | - | | Atlético Tucumán | 1 | : | 2 |
| Group C |
Apr 19 • 02:45 | Club Libertad | | - | | CA Peñarol | 2 | : | 1 |
| Group D |
Apr 19 • 02:45 | Flamengo | | - | | Independiente Santa Fe | 1 | : | 1 |
| Group G |
Apr 19 • 02:45 | Independiente | | - | | Corinthians | 0 | : | 1 |
| Group E |
Apr 20 • 00:15 | Racing Club | | - | | CR Vasco da Gama | 4 | : | 0 |
| Group D |
Apr 20 • 02:30 | CS Emelec | | - | | River Plate | 0 | : | 1 |
| Group E |
Apr 20 • 02:30 | Universidad de Chile | | - | | Cruzeiro EC | 0 | : | 0 |
| Group H |
Apr 20 • 02:30 | Alianza Lima | | - | | Atlético Junior | 0 | : | 2 |
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| Group G |
Apr 25 • 00:15 | Deportivo Lara | | - | | Los Millonarios | 2 | : | 1 |
| Group B |
Apr 25 • 02:30 | Atlético Nacional | | - | | Club Bolívar | 4 | : | 1 |
| Group F |
Apr 25 • 02:30 | Santos FC | | - | | Estudiantes de La Plata | 2 | : | 0 |
| Group C |
Apr 26 • 00:15 | Atlético Tucumán | | - | | The Strongest | 3 | : | 0 |
| Group F |
Apr 26 • 00:15 | Club Nacional Montevideo | | - | | Cusco FC | 4 | : | 0 |
| Group A |
Apr 26 • 02:45 | Monagas SC | | - | | Defensor Sporting | 1 | : | 0 |
| Group D |
Apr 26 • 02:45 | Independiente Santa Fe | | - | | Flamengo | 0 | : | 0 |
| Group H |
Apr 26 • 02:45 | Boca Juniors | | - | | SE Palmeiras | 0 | : | 2 |
| Group D |
Apr 27 • 00:15 | River Plate | | - | | CS Emelec | 2 | : | 1 |
| Group E |
Apr 27 • 00:15 | Cruzeiro EC | | - | | Universidad de Chile | 7 | : | 0 |
| Group C |
Apr 27 • 02:30 | CA Peñarol | | - | | Club Libertad | 2 | : | 0 |
| Group E |
Apr 27 • 02:30 | CR Vasco da Gama | | - | | Racing Club | 1 | : | 1 |
| Group H |
Apr 27 • 02:30 | Atlético Junior | | - | | Alianza Lima | 1 | : | 0 |
| Group A |
May 02 • 00:15 | Grêmio Porto Alegrense | | - | | Cerro Porteño | 5 | : | 0 |
| Group B |
May 03 • 02:45 | Delfín SC | | - | | Colo-Colo | 1 | : | 2 |
| Group G |
May 03 • 02:45 | Corinthians | | - | | Independiente | 1 | : | 2 |
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| Group F |
May 02 • 00:15 | Cusco FC | | - | | Estudiantes de La Plata | 0 | : | 0 |
| Group F |
May 02 • 02:30 | Club Nacional Montevideo | | - | | Santos FC | 1 | : | 0 |
| Group C |
May 03 • 00:15 | Atlético Tucumán | | - | | CA Peñarol | 1 | : | 0 |
| Group H |
May 03 • 00:15 | Atlético Junior | | - | | Boca Juniors | 1 | : | 1 |
| Group E |
May 03 • 02:45 | CR Vasco da Gama | | - | | Cruzeiro EC | 0 | : | 4 |
| Group E |
May 04 • 00:15 | Racing Club | | - | | Universidad de Chile | 1 | : | 0 |
| Group C |
May 04 • 02:30 | The Strongest | | - | | Club Libertad | 1 | : | 3 |
| Group D |
May 04 • 02:30 | Independiente Santa Fe | | - | | River Plate | 0 | : | 1 |
| Group H |
May 04 • 02:30 | Alianza Lima | | - | | SE Palmeiras | 1 | : | 3 |
| Group A |
May 16 • 00:15 | Defensor Sporting | | - | | Cerro Porteño | 0 | : | 1 |
| Group B |
May 16 • 00:15 | Delfín SC | | - | | Atlético Nacional | 1 | : | 0 |
| Group A |
May 16 • 02:30 | Monagas SC | | - | | Grêmio Porto Alegrense | 1 | : | 2 |
| Group B |
May 16 • 02:30 | Colo-Colo | | - | | Club Bolívar | 2 | : | 0 |
| Group D |
May 17 • 02:45 | Flamengo | | - | | CS Emelec | 2 | : | 0 |
| Group G |
May 18 • 02:30 | Deportivo Lara | | - | | Corinthians | 2 | : | 7 |
| Group G |
May 18 • 02:30 | Los Millonarios | | - | | Independiente | 1 | : | 1 |
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| Group H |
May 17 • 02:45 | Boca Juniors | | - | | Alianza Lima | 5 | : | 0 |
| Group H |
May 17 • 02:45 | SE Palmeiras | | - | | Atlético Junior | 3 | : | 1 |
| Group C |
May 18 • 00:15 | CA Peñarol | | - | | The Strongest | 2 | : | 0 |
| Group C |
May 18 • 00:15 | Club Libertad | | - | | Atlético Tucumán | 0 | : | 0 |
| Group E |
May 23 • 02:30 | Cruzeiro EC | | - | | Racing Club | 2 | : | 1 |
| Group E |
May 23 • 02:30 | Universidad de Chile | | - | | CR Vasco da Gama | 0 | : | 2 |
| Group A |
May 24 • 00:15 | Grêmio Porto Alegrense | | - | | Defensor Sporting | 1 | : | 0 |
| Group A |
May 24 • 00:15 | Cerro Porteño | | - | | Monagas SC | 3 | : | 2 |
| Group D |
May 24 • 02:45 | River Plate | | - | | Flamengo | 0 | : | 0 |
| Group D |
May 24 • 02:45 | CS Emelec | | - | | Independiente Santa Fe | 0 | : | 3 |
| Group F |
May 25 • 00:15 | Santos FC | | - | | Cusco FC | 0 | : | 0 |
| Group F |
May 25 • 00:15 | Estudiantes de La Plata | | - | | Club Nacional Montevideo | 3 | : | 1 |
| Group B |
May 25 • 02:30 | Club Bolívar | | - | | Delfín SC | 2 | : | 1 |
| Group B |
May 25 • 02:30 | Atlético Nacional | | - | | Colo-Colo | 0 | : | 0 |
| Group G |
May 25 • 02:30 | Corinthians | | - | | Los Millonarios | 0 | : | 1 |
| Group G |
May 25 • 02:30 | Independiente | | - | | Deportivo Lara | 2 | : | 0 |
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| Aug 08 • 02:45 | Estudiantes de La Plata | | - | | Grêmio Porto Alegrense | 2 | : | 1 |
| Aug 09 • 00:30 | Boca Juniors | | - | | Club Libertad | 2 | : | 0 |
| Aug 09 • 02:45 | Flamengo | | - | | Cruzeiro EC | 0 | : | 2 |
| Aug 09 • 02:45 | Colo-Colo | | - | | Corinthians | 1 | : | 0 |
| Aug 10 • 00:30 | Racing Club | | - | | River Plate | 0 | : | 0 |
| Aug 10 • 02:45 | Cerro Porteño | | - | | SE Palmeiras | 0 | : | 2 |
| Aug 10 • 02:45 | Atlético Tucumán | | - | | Atlético Nacional | 2 | : | 0 |
| Aug 22 • 02:45 | Independiente | | - | | Santos FC | 0 | : | 0 |
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| Aug 29 • 00:30 | Santos FC | | - | | Independiente | 0 | : | 0 |
| Aug 29 • 02:45 | Grêmio Porto Alegrense | | - | | Estudiantes de La Plata | 2 | : | 1 |
| Aug 29 • 02:45 | Atlético Nacional | | - | | Atlético Tucumán | 1 | : | 0 |
| Aug 30 • 00:30 | River Plate | | - | | Racing Club | 3 | : | 0 |
| Aug 30 • 02:45 | Cruzeiro EC | | - | | Flamengo | 0 | : | 1 |
| Aug 30 • 02:45 | Corinthians | | - | | Colo-Colo | 2 | : | 1 |
| Aug 31 • 00:30 | Club Libertad | | - | | Boca Juniors | 2 | : | 4 |
| Aug 31 • 02:45 | SE Palmeiras | | - | | Cerro Porteño | 0 | : | 1 |
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| Sep 19 • 02:45 | Atlético Tucumán | | - | | Grêmio Porto Alegrense | 0 | : | 2 |
| Sep 20 • 00:30 | Independiente | | - | | River Plate | 0 | : | 0 |
| Sep 20 • 02:45 | Boca Juniors | | - | | Cruzeiro EC | 2 | : | 0 |
| Sep 21 • 02:45 | Colo-Colo | | - | | SE Palmeiras | 0 | : | 2 |
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| Oct 03 • 00:30 | River Plate | | - | | Independiente | 3 | : | 1 |
| Oct 03 • 02:45 | Grêmio Porto Alegrense | | - | | Atlético Tucumán | 4 | : | 0 |
| Oct 04 • 02:45 | SE Palmeiras | | - | | Colo-Colo | 2 | : | 0 |
| Oct 05 • 02:45 | Cruzeiro EC | | - | | Boca Juniors | 1 | : | 1 |
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| Oct 24 • 02:45 | River Plate | | - | | Grêmio Porto Alegrense | 0 | : | 1 |
| Oct 25 • 02:45 | Boca Juniors | | - | | SE Palmeiras | 2 | : | 0 |
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| Oct 31 • 01:45 | Grêmio Porto Alegrense | | - | | River Plate | 1 | : | 2 |
| Nov 01 • 01:45 | SE Palmeiras | | - | | Boca Juniors | 2 | : | 2 |
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| Nov 11 • 20:00 | Boca Juniors | | - | | River Plate | 2 | : | 2 |
| Nov 25 • 21:00 | River Plate | | - | | Boca Juniors | 3 | : | 1 |
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