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| Pool A |
Dec 11 • 18:30 | Northampton Saints |  | - |  | Union Bordeaux Bègles | 12 | : | 16 |
| Pool B |
Dec 11 • 21:00 | Ulster Rugby |  | - |  | Stade Toulousain | 22 | : | 29 |
| Pool B |
Dec 12 • 14:00 | Bristol Bears |  | - |  | ASM Clermont Auvergne | 38 | : | 51 |
| Pool A |
Dec 12 • 16:15 | RC Toulonnais |  | - |  | Sale Sharks | 26 | : | 14 |
| Pool A |
Dec 12 • 16:15 | Bath Rugby |  | - |  | Scarlets | 19 | : | 23 |
| Pool A |
Dec 12 • 18:30 | Dragons |  | - |  | Wasps RFC | 8 | : | 24 |
| Pool A |
Dec 12 • 18:30 | Montpellier Hérault Rugby |  | - |  | Leinster Rugby | 14 | : | 35 |
| Pool A |
Dec 12 • 21:00 | Edinburgh Rugby |  | - |  | Stade Rochelais | 8 | : | 13 |
| Pool B |
Dec 13 • 14:00 | Lyon OU |  | - |  | Gloucester Rugby | 55 | : | 10 |
| Pool B |
Dec 13 • 16:15 | Racing 92 |  | - |  | Connacht Rugby | 26 | : | 22 |
| Pool B |
Dec 13 • 16:15 | Exeter Chiefs |  | - |  | Glasgow Warriors | 42 | : | 0 |
| Pool B |
Dec 13 • 18:30 | Munster Rugby |  | - |  | Harlequins | 21 | : | 7 |
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| Pool A |
Dec 18 • 00:00 | Scarlets | | - | | RC Toulonnais | 28 | : | 0 |
| Pool A |
Dec 18 • 21:00 | Wasps RFC | | - | | Montpellier Hérault Rugby | 33 | : | 14 |
| Pool A |
Dec 19 • 00:00 | Stade Rochelais | | - | | Bath Rugby | 28 | : | 0 |
| Pool B |
Dec 19 • 00:00 | Glasgow Warriors | | - | | Lyon OU | 0 | : | 28 |
| Pool B |
Dec 19 • 00:00 | Stade Toulousain | | - | | Exeter Chiefs | 28 | : | 0 |
| Pool A |
Dec 19 • 14:00 | Leinster Rugby | | - | | Northampton Saints | 35 | : | 19 |
| Pool B |
Dec 19 • 16:15 | Gloucester Rugby | | - | | Ulster Rugby | 38 | : | 34 |
| Pool B |
Dec 19 • 18:30 | ASM Clermont Auvergne | | - | | Munster Rugby | 31 | : | 39 |
| Pool A |
Dec 19 • 21:00 | Sale Sharks | | - | | Edinburgh Rugby | 15 | : | 16 |
| Pool A |
Dec 19 • 21:00 | Union Bordeaux Bègles | | - | | Dragons | 47 | : | 8 |
| Pool B |
Dec 20 • 16:15 | Harlequins | | - | | Racing 92 | 7 | : | 49 |
| Pool B |
Dec 20 • 18:30 | Connacht Rugby | | - | | Bristol Bears | 18 | : | 27 |
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| Apr 02 • 18:30 | Leinster Rugby | | - | | RC Toulonnais | 0 | : | 0 |
| Apr 02 • 21:00 | Gloucester Rugby | | - | | Stade Rochelais | 16 | : | 27 |
| Apr 03 • 13:30 | Wasps RFC | | - | | ASM Clermont Auvergne | 25 | : | 27 |
| Apr 03 • 16:00 | Munster Rugby | | - | | Stade Toulousain | 33 | : | 40 |
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| Apr 03 • 18:30 | Exeter Chiefs | | - | | Lyon OU | 47 | : | 25 |
| Apr 04 • 13:30 | Racing 92 | | - | | Edinburgh Rugby | 56 | : | 3 |
| Apr 04 • 16:00 | Union Bordeaux Bègles | | - | | Bristol Bears | 36 | : | 17 |
| Apr 04 • 18:30 | Scarlets | | - | | Sale Sharks | 14 | : | 57 |
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| Apr 10 • 16:00 | Stade Rochelais | | - | | Sale Sharks | 45 | : | 21 |
| Apr 10 • 18:30 | Exeter Chiefs | | - | | Leinster Rugby | 22 | : | 34 |
| Apr 11 • 13:30 | Union Bordeaux Bègles | | - | | Racing 92 | 24 | : | 21 |
| Apr 11 • 16:00 | ASM Clermont Auvergne | | - | | Stade Toulousain | 12 | : | 21 |
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| May 01 • 16:00 | Stade Toulousain | | - | | Union Bordeaux Bègles | 21 | : | 9 |
| May 02 • 16:00 | Stade Rochelais | | - | | Leinster Rugby | 32 | : | 23 |
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| May 22 • 17:45 | Stade Toulousain | | - | | Stade Rochelais | 22 | : | 17 |
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