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| Sep 10 • 16:00 | Exeter Chiefs |  | - |  | Leicester Tigers | 24 | : | 20 |
| Sep 10 • 16:00 | Newcastle Falcons |  | - |  | Harlequins | 31 | : | 40 |
| Sep 10 • 18:30 | Bristol Bears |  | - |  | Bath Rugby | 31 | : | 29 |
| Sep 11 • 16:00 | Sale Sharks |  | - |  | Northampton Saints | 29 | : | 22 |
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| Sep 17 • 15:00 | Northampton Saints | | - |  | London Irish | 38 | : | 22 |
| Sep 17 • 16:00 | Bath Rugby | | - | | Sale Sharks | 20 | : | 37 |
| Sep 17 • 16:00 | Harlequins | | - |  | Saracens | 27 | : | 30 |
| Sep 17 • 16:00 | Leicester Tigers | | - | | Newcastle Falcons | 36 | : | 21 |
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| Sep 24 • 16:00 | Bristol Bears | | - | | London Irish | 40 | : | 36 |
| Sep 24 • 16:00 | Northampton Saints | | - | | Leicester Tigers | 21 | : | 41 |
| Sep 24 • 16:00 | Saracens | | - |  | Gloucester Rugby | 41 | : | 39 |
| Sep 25 • 16:00 | Exeter Chiefs | | - | | Harlequins | 43 | : | 42 |
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| Sep 30 • 20:45 | Newcastle Falcons | | - | | Bristol Bears | 30 | : | 15 |
| Oct 01 • 16:00 | London Irish | | - | | Bath Rugby | 47 | : | 38 |
| Oct 01 • 16:00 | Sale Sharks | | - | | Exeter Chiefs | 28 | : | 20 |
| Oct 01 • 16:00 | Saracens | | - | | Leicester Tigers | 51 | : | 18 |
| Oct 02 • 16:00 | Harlequins | | - | | Northampton Saints | 35 | : | 29 |
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| Oct 07 • 20:45 | Bristol Bears | | - | | Exeter Chiefs | 14 | : | 50 |
| Oct 08 • 16:00 | Bath Rugby | | - | | Gloucester Rugby | 17 | : | 21 |
| Oct 08 • 16:00 | Leicester Tigers | | - | | Sale Sharks | 16 | : | 26 |
| Oct 09 • 16:00 | Newcastle Falcons | | - | | Saracens | 14 | : | 34 |
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| Oct 14 • 20:45 | Sale Sharks | | - | | London Irish | 37 | : | 14 |
| Oct 15 • 16:00 | Gloucester Rugby | | - | | Bristol Bears | 31 | : | 28 |
| Oct 15 • 16:00 | Northampton Saints | | - | | Newcastle Falcons | 32 | : | 31 |
| Oct 15 • 16:00 | Saracens | | - | | Bath Rugby | 37 | : | 31 |
| Oct 16 • 16:00 | Harlequins | | - | | Leicester Tigers | 19 | : | 27 |
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| Oct 21 • 20:45 | London Irish | | - | | Gloucester Rugby | 21 | : | 22 |
| Oct 22 • 16:00 | Bath Rugby | | - | | Northampton Saints | 27 | : | 14 |
| Oct 22 • 16:00 | Exeter Chiefs | | - | | Saracens | 20 | : | 22 |
| Oct 23 • 16:00 | Sale Sharks | | - | | Harlequins | 13 | : | 29 |
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| Oct 28 • 20:45 | Gloucester Rugby | | - | | Exeter Chiefs | 38 | : | 22 |
| Oct 29 • 16:00 | Harlequins | | - | | London Irish | 26 | : | 24 |
| Oct 29 • 16:00 | Northampton Saints | | - | | Bristol Bears | 45 | : | 31 |
| Oct 30 • 16:00 | Saracens | | - | | Sale Sharks | 33 | : | 22 |
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| Nov 04 • 20:45 | Northampton Saints | | - | | Exeter Chiefs | 26 | : | 19 |
| Nov 05 • 14:00 | Sale Sharks | | - | | Gloucester Rugby | 27 | : | 17 |
| Nov 05 • 16:00 | Newcastle Falcons | | - | | Bath Rugby | 10 | : | 17 |
| Nov 05 • 18:00 | Bristol Bears | | - | | Saracens | 10 | : | 25 |
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| Nov 11 • 20:45 | Bath Rugby | | - | | Leicester Tigers | 19 | : | 18 |
| Nov 12 • 16:00 | Gloucester Rugby | | - | | Newcastle Falcons | 21 | : | 27 |
| Nov 12 • 18:00 | Exeter Chiefs | | - | | London Irish | 22 | : | 17 |
| Nov 13 • 13:15 | Saracens | | - | | Northampton Saints | 45 | : | 39 |
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| Nov 25 • 20:45 | Harlequins | | - | | Gloucester Rugby | 21 | : | 12 |
| Nov 25 • 20:45 | Newcastle Falcons | | - | | Exeter Chiefs | 24 | : | 21 |
| Nov 26 • 14:00 | Sale Sharks | | - | | Bristol Bears | 25 | : | 20 |
| Nov 27 • 16:00 | Leicester Tigers | | - | | London Irish | 33 | : | 31 |
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| Dec 02 • 20:45 | Bath Rugby | | - | | Harlequins | 13 | : | 19 |
| Dec 03 • 16:00 | London Irish | | - | | Newcastle Falcons | 39 | : | 17 |
| Dec 03 • 18:30 | Gloucester Rugby | | - | | Northampton Saints | 34 | : | 19 |
| Dec 03 • 21:00 | Bristol Bears | | - | | Leicester Tigers | 26 | : | 26 |
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| Dec 23 • 20:45 | London Irish | | - | | Saracens | 29 | : | 20 |
| Dec 23 • 20:45 | Newcastle Falcons | | - | | Sale Sharks | 20 | : | 14 |
| Dec 24 • 16:00 | Exeter Chiefs | | - | | Bath Rugby | 20 | : | 15 |
| Dec 24 • 16:00 | Leicester Tigers | | - | | Gloucester Rugby | 28 | : | 13 |
| Dec 27 • 17:15 | Harlequins | | - | | Bristol Bears | 12 | : | 15 |
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| Dec 30 • 20:45 | Sale Sharks | | - | | Leicester Tigers | 40 | : | 5 |
| Dec 31 • 16:00 | Bath Rugby | | - | | Newcastle Falcons | 24 | : | 16 |
| Dec 31 • 16:00 | Saracens | | - | | Exeter Chiefs | 35 | : | 3 |
| Dec 31 • 16:00 | Gloucester Rugby | | - | | London Irish | 8 | : | 6 |
| Jan 01 • 16:00 | Northampton Saints | | - | | Harlequins | 46 | : | 17 |
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| Jan 06 • 20:45 | Gloucester Rugby | | - | | Saracens | 16 | : | 19 |
| Jan 07 • 15:00 | Newcastle Falcons | | - | | Leicester Tigers | 45 | : | 26 |
| Jan 07 • 17:30 | Exeter Chiefs | | - | | Northampton Saints | 35 | : | 12 |
| Jan 08 • 16:00 | Harlequins | | - | | Sale Sharks | 16 | : | 24 |
| Jan 08 • 16:00 | London Irish | | - | | Bristol Bears | 23 | : | 7 |
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| Jan 27 • 20:45 | Sale Sharks | | - | | Bath Rugby | 30 | : | 27 |
| Jan 28 • 15:00 | Leicester Tigers | | - | | Northampton Saints | 18 | : | 19 |
| Jan 28 • 16:00 | Saracens | | - | | Bristol Bears | 20 | : | 19 |
| Jan 28 • 17:30 | Exeter Chiefs | | - | | Gloucester Rugby | 24 | : | 17 |
| Jan 29 • 16:00 | London Irish | | - | | Harlequins | 42 | : | 24 |
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| Feb 17 • 20:45 | Bristol Bears | | - | | Newcastle Falcons | 30 | : | 12 |
| Feb 17 • 20:45 | Gloucester Rugby | | - | | Harlequins | 28 | : | 26 |
| Feb 18 • 16:00 | Bath Rugby | | - | | London Irish | 10 | : | 25 |
| Feb 18 • 16:00 | Northampton Saints | | - | | Sale Sharks | 38 | : | 34 |
| Feb 19 • 16:00 | Leicester Tigers | | - | | Saracens | 24 | : | 18 |
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| Feb 24 • 20:45 | Bath Rugby | | - | | Bristol Bears | 13 | : | 15 |
| Feb 25 • 15:30 | Saracens | | - | | Newcastle Falcons | 29 | : | 23 |
| Feb 25 • 15:45 | Northampton Saints | | - | | Gloucester Rugby | 41 | : | 34 |
| Feb 25 • 20:30 | London Irish | | - | | Leicester Tigers | 22 | : | 25 |
| Feb 26 • 14:00 | Exeter Chiefs | | - | | Sale Sharks | 24 | : | 22 |
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| Mar 03 • 20:45 | Bristol Bears | | - | | Northampton Saints | 62 | : | 8 |
| Mar 04 • 16:00 | Leicester Tigers | | - | | Bath Rugby | 48 | : | 27 |
| Mar 04 • 18:15 | Harlequins | | - | | Exeter Chiefs | 40 | : | 5 |
| Mar 05 • 16:00 | Newcastle Falcons | | - | | London Irish | 19 | : | 34 |
| Mar 05 • 16:00 | Sale Sharks | | - | | Saracens | 35 | : | 24 |
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| Mar 10 • 20:45 | Northampton Saints | | - | | Bath Rugby | 45 | : | 26 |
| Mar 11 • 15:30 | Exeter Chiefs | | - | | Newcastle Falcons | 24 | : | 5 |
| Mar 12 • 14:00 | London Irish | | - | | Sale Sharks | 36 | : | 18 |
| Mar 12 • 14:00 | Gloucester Rugby | | - | | Leicester Tigers | 5 | : | 26 |
| Mar 12 • 16:00 | Bristol Bears | | - | | Harlequins | 51 | : | 26 |
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| Mar 24 • 20:45 | Newcastle Falcons | | - | | Gloucester Rugby | 17 | : | 12 |
| Mar 25 • 13:30 | Leicester Tigers | | - | | Bristol Bears | 46 | : | 24 |
| Mar 25 • 16:00 | Saracens | | - | | Harlequins | 36 | : | 24 |
| Mar 25 • 18:30 | London Irish | | - | | Northampton Saints | 37 | : | 22 |
| Mar 26 • 16:00 | Bath Rugby | | - | | Exeter Chiefs | 36 | : | 19 |
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| Apr 14 • 20:45 | Bristol Bears | | - | | Sale Sharks | 20 | : | 36 |
| Apr 14 • 20:45 | Gloucester Rugby | | - | | Bath Rugby | 24 | : | 33 |
| Apr 15 • 16:00 | Harlequins | | - | | Newcastle Falcons | 48 | : | 20 |
| Apr 15 • 16:00 | Northampton Saints | | - | | Saracens | 38 | : | 29 |
| Apr 16 • 16:00 | Leicester Tigers | | - | | Exeter Chiefs | 62 | : | 19 |
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| Apr 21 • 20:45 | Newcastle Falcons | | - | | Northampton Saints | 5 | : | 66 |
| Apr 22 • 16:00 | Exeter Chiefs | | - | | Bristol Bears | 22 | : | 21 |
| Apr 22 • 16:00 | Harlequins | | - | | Bath Rugby | 35 | : | 45 |
| Apr 22 • 18:30 | Gloucester Rugby | | - | | Sale Sharks | 22 | : | 25 |
| Apr 23 • 16:00 | Saracens | | - | | London Irish | 45 | : | 21 |
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| May 06 • 17:00 | London Irish | | - | | Exeter Chiefs | 17 | : | 14 |
| May 06 • 17:00 | Bristol Bears | | - | | Gloucester Rugby | 36 | : | 21 |
| May 06 • 17:00 | Sale Sharks | | - | | Newcastle Falcons | 54 | : | 12 |
| May 06 • 17:00 | Bath Rugby | | - | | Saracens | 61 | : | 29 |
| May 06 • 17:00 | Leicester Tigers | | - | | Harlequins | 17 | : | 20 |
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| May 13 • 16:30 | Saracens | | - | | Northampton Saints | 38 | : | 15 |
| May 14 • 16:00 | Sale Sharks | | - | | Leicester Tigers | 21 | : | 13 |
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| May 27 • 16:00 | Saracens | | - | | Sale Sharks | 35 | : | 25 |
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