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| Group A |
Sep 16 • 20:45 | Chelsea FC |  | - |  | Girondins Bordeaux | 4 | : | 0 |
| Group A |
Sep 16 • 20:45 | AS Roma |  | - |  | CFR Cluj | 1 | : | 2 |
| Group B |
Sep 16 • 20:45 | Werder Bremen |  | - |  | Anorthosis Famagusta | 0 | : | 0 |
| Group B |
Sep 16 • 20:45 | Panathinaikos FC |  | - |  | Inter Milan | 0 | : | 2 |
| Group C |
Sep 16 • 20:45 | FC Barcelona |  | - |  | Sporting CP | 3 | : | 1 |
| Group C |
Sep 16 • 20:45 | FC Basel |  | - |  | Shakhtar Donetsk | 1 | : | 2 |
| Group D |
Sep 16 • 20:45 | PSV Eindhoven |  | - |  | Atlético Madrid | 0 | : | 3 |
| Group D |
Sep 16 • 20:45 | Olympique Marseille |  | - |  | Liverpool FC | 1 | : | 2 |
| Group E |
Sep 17 • 20:45 | Manchester United |  | - |  | Villarreal CF | 0 | : | 0 |
| Group E |
Sep 17 • 20:45 | Celtic FC |  | - |  | Aalborg BK | 0 | : | 0 |
| Group F |
Sep 17 • 20:45 | Olympique Lyon |  | - |  | ACF Fiorentina | 2 | : | 2 |
| Group F |
Sep 17 • 20:45 | FCSB |  | - |  | Bayern Munich | 0 | : | 1 |
| Group G |
Sep 17 • 20:45 | FC Porto |  | - |  | Fenerbahçe SK | 3 | : | 1 |
| Group G |
Sep 17 • 20:45 | Dynamo Kiev |  | - |  | Arsenal FC | 1 | : | 1 |
| Group H |
Sep 17 • 20:45 | Real Madrid |  | - |  | FC BATE Borisov | 2 | : | 0 |
| Group H |
Sep 17 • 20:45 | Juventus FC |  | - |  | Zenit St. Petersburg | 1 | : | 0 |
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| Group H |
Sep 30 • 18:30 | Zenit St. Petersburg | | - | | Real Madrid | 1 | : | 2 |
| Group E |
Sep 30 • 20:45 | Villarreal CF | | - | | Celtic FC | 1 | : | 0 |
| Group E |
Sep 30 • 20:45 | Aalborg BK | | - | | Manchester United | 0 | : | 3 |
| Group F |
Sep 30 • 20:45 | Bayern Munich | | - | | Olympique Lyon | 1 | : | 1 |
| Group F |
Sep 30 • 20:45 | ACF Fiorentina | | - | | FCSB | 0 | : | 0 |
| Group G |
Sep 30 • 20:45 | Arsenal FC | | - | | FC Porto | 4 | : | 0 |
| Group G |
Sep 30 • 20:45 | Fenerbahçe SK | | - | | Dynamo Kiev | 0 | : | 0 |
| Group H |
Sep 30 • 20:45 | FC BATE Borisov | | - | | Juventus FC | 2 | : | 2 |
| Group A |
Oct 01 • 20:45 | Girondins Bordeaux | | - | | AS Roma | 1 | : | 3 |
| Group A |
Oct 01 • 20:45 | CFR Cluj | | - | | Chelsea FC | 0 | : | 0 |
| Group B |
Oct 01 • 20:45 | Inter Milan | | - | | Werder Bremen | 1 | : | 1 |
| Group B |
Oct 01 • 20:45 | Anorthosis Famagusta | | - | | Panathinaikos FC | 3 | : | 1 |
| Group C |
Oct 01 • 20:45 | Sporting CP | | - | | FC Basel | 2 | : | 0 |
| Group C |
Oct 01 • 20:45 | Shakhtar Donetsk | | - | | FC Barcelona | 1 | : | 2 |
| Group D |
Oct 01 • 20:45 | Liverpool FC | | - | | PSV Eindhoven | 3 | : | 1 |
| Group D |
Oct 01 • 20:45 | Atlético Madrid | | - | | Olympique Marseille | 2 | : | 1 |
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| Group H |
Oct 21 • 18:30 | Zenit St. Petersburg | | - | | FC BATE Borisov | 1 | : | 1 |
| Group E |
Oct 21 • 20:45 | Manchester United | | - | | Celtic FC | 3 | : | 0 |
| Group E |
Oct 21 • 20:45 | Villarreal CF | | - | | Aalborg BK | 6 | : | 3 |
| Group F |
Oct 21 • 20:45 | Bayern Munich | | - | | ACF Fiorentina | 3 | : | 0 |
| Group F |
Oct 21 • 20:45 | FCSB | | - | | Olympique Lyon | 3 | : | 5 |
| Group G |
Oct 21 • 20:45 | FC Porto | | - | | Dynamo Kiev | 0 | : | 1 |
| Group G |
Oct 21 • 20:45 | Fenerbahçe SK | | - | | Arsenal FC | 2 | : | 5 |
| Group H |
Oct 21 • 20:45 | Juventus FC | | - | | Real Madrid | 2 | : | 1 |
| Group A |
Oct 22 • 20:45 | Chelsea FC | | - | | AS Roma | 1 | : | 0 |
| Group A |
Oct 22 • 20:45 | Girondins Bordeaux | | - | | CFR Cluj | 1 | : | 0 |
| Group B |
Oct 22 • 20:45 | Inter Milan | | - | | Anorthosis Famagusta | 1 | : | 0 |
| Group B |
Oct 22 • 20:45 | Panathinaikos FC | | - | | Werder Bremen | 2 | : | 2 |
| Group C |
Oct 22 • 20:45 | FC Basel | | - | | FC Barcelona | 0 | : | 5 |
| Group C |
Oct 22 • 20:45 | Shakhtar Donetsk | | - | | Sporting CP | 0 | : | 1 |
| Group D |
Oct 22 • 20:45 | PSV Eindhoven | | - | | Olympique Marseille | 2 | : | 0 |
| Group D |
Oct 22 • 20:45 | Atlético Madrid | | - | | Liverpool FC | 1 | : | 1 |
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| Group A |
Nov 04 • 20:45 | AS Roma | | - | | Chelsea FC | 3 | : | 1 |
| Group A |
Nov 04 • 20:45 | CFR Cluj | | - | | Girondins Bordeaux | 1 | : | 2 |
| Group B |
Nov 04 • 20:45 | Werder Bremen | | - | | Panathinaikos FC | 0 | : | 3 |
| Group B |
Nov 04 • 20:45 | Anorthosis Famagusta | | - | | Inter Milan | 3 | : | 3 |
| Group C |
Nov 04 • 20:45 | FC Barcelona | | - | | FC Basel | 1 | : | 1 |
| Group C |
Nov 04 • 20:45 | Sporting CP | | - | | Shakhtar Donetsk | 1 | : | 0 |
| Group D |
Nov 04 • 20:45 | Liverpool FC | | - | | Atlético Madrid | 1 | : | 1 |
| Group D |
Nov 04 • 20:45 | Olympique Marseille | | - | | PSV Eindhoven | 3 | : | 0 |
| Group E |
Nov 05 • 20:45 | Celtic FC | | - | | Manchester United | 1 | : | 1 |
| Group E |
Nov 05 • 20:45 | Aalborg BK | | - | | Villarreal CF | 2 | : | 2 |
| Group F |
Nov 05 • 20:45 | Olympique Lyon | | - | | FCSB | 2 | : | 0 |
| Group F |
Nov 05 • 20:45 | ACF Fiorentina | | - | | Bayern Munich | 1 | : | 1 |
| Group G |
Nov 05 • 20:45 | Arsenal FC | | - | | Fenerbahçe SK | 0 | : | 0 |
| Group G |
Nov 05 • 20:45 | Dynamo Kiev | | - | | FC Porto | 1 | : | 2 |
| Group H |
Nov 05 • 20:45 | Real Madrid | | - | | Juventus FC | 0 | : | 2 |
| Group H |
Nov 05 • 20:45 | FC BATE Borisov | | - | | Zenit St. Petersburg | 0 | : | 2 |
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| Group H |
Nov 25 • 18:30 | Zenit St. Petersburg | | - | | Juventus FC | 0 | : | 0 |
| Group E |
Nov 25 • 20:45 | Villarreal CF | | - | | Manchester United | 0 | : | 0 |
| Group E |
Nov 25 • 20:45 | Aalborg BK | | - | | Celtic FC | 2 | : | 1 |
| Group F |
Nov 25 • 20:45 | Bayern Munich | | - | | FCSB | 3 | : | 0 |
| Group F |
Nov 25 • 20:45 | ACF Fiorentina | | - | | Olympique Lyon | 1 | : | 2 |
| Group G |
Nov 25 • 20:45 | Arsenal FC | | - | | Dynamo Kiev | 1 | : | 0 |
| Group G |
Nov 25 • 20:45 | Fenerbahçe SK | | - | | FC Porto | 1 | : | 2 |
| Group H |
Nov 25 • 20:45 | FC BATE Borisov | | - | | Real Madrid | 0 | : | 1 |
| Group A |
Nov 26 • 20:45 | Girondins Bordeaux | | - | | Chelsea FC | 1 | : | 1 |
| Group A |
Nov 26 • 20:45 | CFR Cluj | | - | | AS Roma | 1 | : | 3 |
| Group B |
Nov 26 • 20:45 | Inter Milan | | - | | Panathinaikos FC | 0 | : | 1 |
| Group B |
Nov 26 • 20:45 | Anorthosis Famagusta | | - | | Werder Bremen | 2 | : | 2 |
| Group C |
Nov 26 • 20:45 | Sporting CP | | - | | FC Barcelona | 2 | : | 5 |
| Group C |
Nov 26 • 20:45 | Shakhtar Donetsk | | - | | FC Basel | 5 | : | 0 |
| Group D |
Nov 26 • 20:45 | Liverpool FC | | - | | Olympique Marseille | 1 | : | 0 |
| Group D |
Nov 26 • 20:45 | Atlético Madrid | | - | | PSV Eindhoven | 2 | : | 1 |
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| Group A |
Dec 09 • 20:45 | Chelsea FC | | - | | CFR Cluj | 2 | : | 1 |
| Group A |
Dec 09 • 20:45 | AS Roma | | - | | Girondins Bordeaux | 2 | : | 0 |
| Group B |
Dec 09 • 20:45 | Werder Bremen | | - | | Inter Milan | 2 | : | 1 |
| Group B |
Dec 09 • 20:45 | Panathinaikos FC | | - | | Anorthosis Famagusta | 1 | : | 0 |
| Group C |
Dec 09 • 20:45 | FC Barcelona | | - | | Shakhtar Donetsk | 2 | : | 3 |
| Group C |
Dec 09 • 20:45 | FC Basel | | - | | Sporting CP | 0 | : | 1 |
| Group D |
Dec 09 • 20:45 | PSV Eindhoven | | - | | Liverpool FC | 1 | : | 3 |
| Group D |
Dec 09 • 20:45 | Olympique Marseille | | - | | Atlético Madrid | 0 | : | 0 |
| Group E |
Dec 10 • 20:45 | Manchester United | | - | | Aalborg BK | 2 | : | 2 |
| Group E |
Dec 10 • 20:45 | Celtic FC | | - | | Villarreal CF | 2 | : | 0 |
| Group F |
Dec 10 • 20:45 | Olympique Lyon | | - | | Bayern Munich | 2 | : | 3 |
| Group F |
Dec 10 • 20:45 | FCSB | | - | | ACF Fiorentina | 0 | : | 1 |
| Group G |
Dec 10 • 20:45 | FC Porto | | - | | Arsenal FC | 2 | : | 0 |
| Group G |
Dec 10 • 20:45 | Dynamo Kiev | | - | | Fenerbahçe SK | 1 | : | 0 |
| Group H |
Dec 10 • 20:45 | Real Madrid | | - | | Zenit St. Petersburg | 3 | : | 0 |
| Group H |
Dec 10 • 20:45 | Juventus FC | | - | | FC BATE Borisov | 0 | : | 0 |
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| Feb 24 • 20:45 | Atlético Madrid | | - | | FC Porto | 2 | : | 2 |
| Feb 24 • 20:45 | Olympique Lyon | | - | | FC Barcelona | 1 | : | 1 |
| Feb 24 • 20:45 | Arsenal FC | | - | | AS Roma | 1 | : | 0 |
| Feb 24 • 20:45 | Inter Milan | | - | | Manchester United | 0 | : | 0 |
| Feb 25 • 20:45 | Chelsea FC | | - | | Juventus FC | 1 | : | 0 |
| Feb 25 • 20:45 | Villarreal CF | | - | | Panathinaikos FC | 1 | : | 1 |
| Feb 25 • 20:45 | Sporting CP | | - | | Bayern Munich | 0 | : | 5 |
| Feb 25 • 20:45 | Real Madrid | | - | | Liverpool FC | 0 | : | 1 |
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| Mar 10 • 20:45 | Juventus FC | | - | | Chelsea FC | 2 | : | 2 |
| Mar 10 • 20:45 | Panathinaikos FC | | - | | Villarreal CF | 1 | : | 2 |
| Mar 10 • 20:45 | Bayern Munich | | - | | Sporting CP | 7 | : | 1 |
| Mar 10 • 20:45 | Liverpool FC | | - | | Real Madrid | 4 | : | 0 |
| Mar 11 • 20:45 | FC Porto | | - | | Atlético Madrid | 0 | : | 0 |
| Mar 11 • 20:45 | FC Barcelona | | - | | Olympique Lyon | 5 | : | 2 |
| Mar 11 • 20:45 | AS Roma | | - | | Arsenal FC | 7 | : | 7 |
| Mar 11 • 20:45 | Manchester United | | - | | Inter Milan | 2 | : | 0 |
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| Apr 07 • 20:45 | Villarreal CF | | - | | Arsenal FC | 1 | : | 1 |
| Apr 07 • 20:45 | Manchester United | | - | | FC Porto | 2 | : | 2 |
| Apr 08 • 20:45 | Liverpool FC | | - | | Chelsea FC | 1 | : | 3 |
| Apr 08 • 20:45 | FC Barcelona | | - | | Bayern Munich | 4 | : | 0 |
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| Apr 14 • 20:45 | Chelsea FC | | - | | Liverpool FC | 4 | : | 4 |
| Apr 14 • 20:45 | Bayern Munich | | - | | FC Barcelona | 1 | : | 1 |
| Apr 15 • 20:45 | Arsenal FC | | - | | Villarreal CF | 3 | : | 0 |
| Apr 15 • 20:45 | FC Porto | | - | | Manchester United | 0 | : | 1 |
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| Apr 28 • 20:45 | FC Barcelona | | - | | Chelsea FC | 0 | : | 0 |
| Apr 29 • 20:45 | Manchester United | | - | | Arsenal FC | 1 | : | 0 |
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| May 05 • 20:45 | Arsenal FC | | - | | Manchester United | 1 | : | 3 |
| May 06 • 20:45 | Chelsea FC | | - | | FC Barcelona | 1 | : | 1 |
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| May 27 • 20:45 | Manchester United | | - | | FC Barcelona | 0 | : | 2 |
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