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| Pool E |
Nov 15 • 20:45 | Gloucester Rugby |  | - |  | Stade Toulousain | 20 | : | 25 |
| Pool B |
Nov 16 • 14:00 | Glasgow Warriors |  | - |  | Sale Sharks | 13 | : | 7 |
| Pool C |
Nov 16 • 14:00 | Bath Rugby |  | - |  | Ulster Rugby | 16 | : | 17 |
| Pool A |
Nov 16 • 16:15 | Leinster Rugby |  | - |  | Benetton Treviso | 33 | : | 19 |
| Pool B |
Nov 16 • 16:15 | Stade Rochelais |  | - |  | Exeter Chiefs | 12 | : | 31 |
| Pool C |
Nov 16 • 18:30 | ASM Clermont Auvergne |  | - |  | Harlequins | 53 | : | 21 |
| Pool D |
Nov 16 • 18:30 | Ospreys |  | - |  | Munster Rugby | 13 | : | 32 |
| Pool A |
Nov 17 • 14:00 | Northampton Saints |  | - |  | Lyon OU | 25 | : | 14 |
| Pool E |
Nov 17 • 14:00 | Connacht Rugby |  | - |  | Montpellier Hérault Rugby | 23 | : | 20 |
| Pool D |
Nov 17 • 16:15 | Racing 92 |  | - |  | Saracens | 30 | : | 10 |
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| Pool C |
Nov 22 • 20:45 | Ulster Rugby | | - | | ASM Clermont Auvergne | 18 | : | 13 |
| Pool A |
Nov 23 • 14:00 | Benetton Treviso | | - | | Northampton Saints | 32 | : | 35 |
| Pool D |
Nov 23 • 14:00 | Saracens | | - | | Ospreys | 44 | : | 3 |
| Pool E |
Nov 23 • 14:00 | Stade Toulousain | | - | | Connacht Rugby | 32 | : | 17 |
| Pool A |
Nov 23 • 16:15 | Lyon OU | | - | | Leinster Rugby | 6 | : | 13 |
| Pool B |
Nov 23 • 16:15 | Exeter Chiefs | | - | | Glasgow Warriors | 34 | : | 18 |
| Pool C |
Nov 23 • 18:30 | Harlequins | | - | | Bath Rugby | 15 | : | 9 |
| Pool D |
Nov 23 • 18:30 | Munster Rugby | | - | | Racing 92 | 21 | : | 21 |
| Pool B |
Nov 24 • 14:00 | Sale Sharks | | - | | Stade Rochelais | 25 | : | 15 |
| Pool E |
Nov 24 • 16:15 | Montpellier Hérault Rugby | | - | | Gloucester Rugby | 30 | : | 27 |
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|
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| Pool C |
Dec 06 • 20:45 | Bath Rugby | | - | | ASM Clermont Auvergne | 17 | : | 34 |
| Pool A |
Dec 07 • 14:00 | Lyon OU | | - | | Benetton Treviso | 28 | : | 0 |
| Pool A |
Dec 07 • 14:00 | Northampton Saints | | - | | Leinster Rugby | 16 | : | 43 |
| Pool B |
Dec 07 • 16:15 | Stade Rochelais | | - | | Glasgow Warriors | 24 | : | 27 |
| Pool C |
Dec 07 • 16:15 | Ulster Rugby | | - | | Harlequins | 25 | : | 24 |
| Pool D |
Dec 07 • 18:30 | Ospreys | | - | | Racing 92 | 19 | : | 40 |
| Pool D |
Dec 07 • 18:30 | Munster Rugby | | - | | Saracens | 10 | : | 3 |
| Pool E |
Dec 08 • 14:00 | Gloucester Rugby | | - | | Connacht Rugby | 26 | : | 17 |
| Pool B |
Dec 08 • 16:15 | Sale Sharks | | - | | Exeter Chiefs | 20 | : | 22 |
| Pool E |
Dec 08 • 16:15 | Stade Toulousain | | - | | Montpellier Hérault Rugby | 23 | : | 9 |
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|
|
| Pool C |
Dec 13 • 20:45 | Harlequins | | - | | Ulster Rugby | 10 | : | 34 |
| Pool D |
Dec 13 • 20:45 | Racing 92 | | - | | Ospreys | 40 | : | 27 |
| Pool A |
Dec 14 • 13:45 | Benetton Treviso | | - | | Lyon OU | 25 | : | 22 |
| Pool E |
Dec 14 • 13:45 | Connacht Rugby | | - | | Gloucester Rugby | 27 | : | 24 |
| Pool D |
Dec 14 • 16:00 | Saracens | | - | | Munster Rugby | 15 | : | 6 |
| Pool E |
Dec 14 • 16:00 | Montpellier Hérault Rugby | | - | | Stade Toulousain | 18 | : | 26 |
| Pool A |
Dec 14 • 18:15 | Leinster Rugby | | - | | Northampton Saints | 50 | : | 21 |
| Pool B |
Dec 14 • 18:15 | Glasgow Warriors | | - | | Stade Rochelais | 7 | : | 12 |
| Pool B |
Dec 15 • 14:00 | Exeter Chiefs | | - | | Sale Sharks | 35 | : | 10 |
| Pool C |
Dec 15 • 16:15 | ASM Clermont Auvergne | | - | | Bath Rugby | 52 | : | 26 |
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|
|
| Pool B |
Jan 10 • 20:45 | Stade Rochelais | | - | | Sale Sharks | 30 | : | 23 |
| Pool C |
Jan 10 • 20:45 | Bath Rugby | | - | | Harlequins | 19 | : | 25 |
| Pool C |
Jan 11 • 14:00 | ASM Clermont Auvergne | | - | | Ulster Rugby | 29 | : | 13 |
| Pool D |
Jan 11 • 14:00 | Ospreys | | - | | Saracens | 15 | : | 22 |
| Pool B |
Jan 11 • 16:15 | Glasgow Warriors | | - | | Exeter Chiefs | 31 | : | 31 |
| Pool E |
Jan 11 • 16:15 | Connacht Rugby | | - | | Stade Toulousain | 7 | : | 21 |
| Pool E |
Jan 11 • 18:30 | Gloucester Rugby | | - | | Montpellier Hérault Rugby | 29 | : | 6 |
| Pool A |
Jan 12 • 14:00 | Northampton Saints | | - | | Benetton Treviso | 33 | : | 20 |
| Pool A |
Jan 12 • 14:00 | Leinster Rugby | | - | | Lyon OU | 42 | : | 14 |
| Pool D |
Jan 12 • 16:15 | Racing 92 | | - | | Munster Rugby | 39 | : | 22 |
|
|
|
| Pool A |
Jan 18 • 14:00 | Benetton Treviso | | - | | Leinster Rugby | 0 | : | 18 |
| Pool A |
Jan 18 • 14:00 | Lyon OU | | - | | Northampton Saints | 24 | : | 36 |
| Pool C |
Jan 18 • 16:15 | Ulster Rugby | | - | | Bath Rugby | 22 | : | 15 |
| Pool C |
Jan 18 • 16:15 | Harlequins | | - | | ASM Clermont Auvergne | 19 | : | 26 |
| Pool B |
Jan 18 • 18:30 | Sale Sharks | | - | | Glasgow Warriors | 7 | : | 45 |
| Pool B |
Jan 18 • 18:30 | Exeter Chiefs | | - | | Stade Rochelais | 33 | : | 14 |
| Pool D |
Jan 19 • 14:00 | Munster Rugby | | - | | Ospreys | 33 | : | 6 |
| Pool D |
Jan 19 • 14:00 | Saracens | | - | | Racing 92 | 27 | : | 24 |
| Pool E |
Jan 19 • 16:15 | Stade Toulousain | | - | | Gloucester Rugby | 35 | : | 14 |
| Pool E |
Jan 19 • 16:15 | Montpellier Hérault Rugby | | - | | Connacht Rugby | 35 | : | 29 |
|
|
|
| Sep 19 • 16:00 | Leinster Rugby | | - | | Saracens | 17 | : | 25 |
| Sep 19 • 18:45 | ASM Clermont Auvergne | | - | | Racing 92 | 27 | : | 36 |
| Sep 20 • 13:30 | Stade Toulousain | | - | | Ulster Rugby | 36 | : | 8 |
| Sep 20 • 18:30 | Exeter Chiefs | | - | | Northampton Saints | 38 | : | 15 |
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| Sep 26 • 14:00 | Racing 92 | | - | | Saracens | 19 | : | 15 |
| Sep 26 • 16:30 | Exeter Chiefs | | - | | Stade Toulousain | 28 | : | 18 |
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| Oct 17 • 17:45 | Racing 92 | | - | | Exeter Chiefs | 27 | : | 31 |
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