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| Jan 25 • 00:15 | Arsenal de Sarandí |  | - |  | Sport Huancayo | 3 | : | 0 |
| Jan 25 • 02:30 | El Nacional |  | - |  | Club Libertad | 1 | : | 0 |
| Jan 25 • 22:50 | Unión Española |  | - |  | UANL Tigres | 1 | : | 0 |
| Jan 26 • 01:00 | Real Potosí |  | - |  | Flamengo | 2 | : | 1 |
| Jan 26 • 01:00 | SC Internacional |  | - |  | Once Caldas | 1 | : | 0 |
| Jan 26 • 23:45 | CA Peñarol |  | - |  | Caracas FC | 4 | : | 0 |
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| Feb 01 • 00:00 | Club Libertad | | - | | El Nacional | 4 | : | 1 |
| Feb 01 • 02:30 | Sport Huancayo | | - | | Arsenal de Sarandí | 1 | : | 1 |
| Feb 02 • 01:00 | Flamengo | | - | | Real Potosí | 2 | : | 0 |
| Feb 02 • 01:00 | Once Caldas | | - | | SC Internacional | 2 | : | 2 |
| Feb 03 • 00:30 | Caracas FC | | - | | CA Peñarol | 1 | : | 1 |
| Feb 03 • 03:00 | UANL Tigres | | - | | Unión Española | 2 | : | 2 |
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| Group G |
Feb 07 • 22:45 | Defensor Sporting |  | - |  | Vélez Sársfield | 0 | : | 3 |
| Group D |
Feb 08 • 01:00 | Fluminense FC |  | - | | Arsenal de Sarandí | 1 | : | 0 |
| Group G |
Feb 08 • 03:15 | Chivas Guadalajara |  | - |  | Deportivo Quito | 1 | : | 1 |
| Group C |
Feb 08 • 22:45 | Unión Española | | - |  | Atlético Junior | 2 | : | 0 |
| Group F |
Feb 08 • 22:45 | Club Nacional Asunción |  | - |  | Cruz Azul | 1 | : | 2 |
| Group E |
Feb 09 • 01:00 | CR Vasco da Gama |  | - |  | Club Nacional Montevideo | 1 | : | 2 |
| Group A |
Feb 09 • 23:00 | SC Internacional | | - |  | Juan Aurich | 2 | : | 0 |
| Group C |
Feb 10 • 01:15 | CD Universidad Católica |  | - |  | Club Bolívar | 1 | : | 1 |
| Group E |
Feb 10 • 01:15 | Club Libertad | | - |  | Alianza Lima | 4 | : | 1 |
| Group B |
Feb 10 • 03:30 | CS Emelec |  | - |  | Olimpia Asunción | 1 | : | 0 |
| Group D |
Feb 15 • 01:15 | Zamora FC |  | - |  | Boca Juniors | 0 | : | 0 |
| Group H |
Feb 15 • 03:30 | Atlético Nacional |  | - |  | Universidad de Chile | 2 | : | 0 |
| Group A |
Feb 15 • 22:45 | The Strongest |  | - |  | Santos FC | 2 | : | 1 |
| Group B |
Feb 16 • 01:00 | CA Lanús |  | - | | Flamengo | 1 | : | 1 |
| Group F |
Feb 16 • 01:00 | Deportivo Táchira |  | - |  | Corinthians | 1 | : | 1 |
| Group H |
Feb 17 • 01:30 | Godoy Cruz |  | - | | CA Peñarol | 1 | : | 0 |
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| Group G |
Feb 14 • 23:00 | Defensor Sporting | | - | | Deportivo Quito | 2 | : | 0 |
| Group E |
Feb 16 • 23:15 | Club Nacional Montevideo | | - | | Club Libertad | 1 | : | 2 |
| Group H |
Feb 21 • 23:15 | CA Peñarol | | - | | Atlético Nacional | 0 | : | 4 |
| Group C |
Feb 22 • 01:30 | Club Bolívar | | - | | Unión Española | 1 | : | 3 |
| Group D |
Feb 22 • 01:30 | Arsenal de Sarandí | | - | | Zamora FC | 3 | : | 0 |
| Group F |
Feb 22 • 03:45 | Cruz Azul | | - | | Deportivo Táchira | 4 | : | 0 |
| Group H |
Feb 22 • 23:45 | Universidad de Chile | | - | | Godoy Cruz | 5 | : | 1 |
| Group G |
Feb 23 • 02:00 | Vélez Sársfield | | - | | Chivas Guadalajara | 3 | : | 0 |
| Group B |
Feb 23 • 23:30 | Olimpia Asunción | | - | | CA Lanús | 2 | : | 1 |
| Group A |
Feb 24 • 01:45 | The Strongest | | - | | Juan Aurich | 2 | : | 1 |
| Group C |
Feb 24 • 01:45 | CD Universidad Católica | | - | | Atlético Junior | 2 | : | 2 |
| Group E |
Mar 07 • 01:45 | CR Vasco da Gama | | - | | Alianza Lima | 3 | : | 2 |
| Group A |
Mar 07 • 23:45 | Santos FC | | - | | SC Internacional | 3 | : | 1 |
| Group D |
Mar 08 • 02:00 | Boca Juniors | | - | | Fluminense FC | 1 | : | 2 |
| Group F |
Mar 08 • 02:00 | Corinthians | | - | | Club Nacional Asunción | 2 | : | 0 |
| Group B |
Mar 08 • 23:30 | Flamengo | | - | | CS Emelec | 1 | : | 0 |
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| Group H |
Mar 06 • 23:30 | CA Peñarol | | - | | Universidad de Chile | 1 | : | 1 |
| Group C |
Mar 07 • 01:45 | Unión Española | | - | | CD Universidad Católica | 1 | : | 1 |
| Group G |
Mar 07 • 23:45 | Deportivo Quito | | - | | Vélez Sársfield | 3 | : | 0 |
| Group H |
Mar 09 • 01:45 | Godoy Cruz | | - | | Atlético Nacional | 4 | : | 4 |
| Group C |
Mar 09 • 04:00 | Atlético Junior | | - | | Club Bolívar | 0 | : | 1 |
| Group B |
Mar 13 • 23:45 | CA Lanús | | - | | CS Emelec | 1 | : | 0 |
| Group F |
Mar 13 • 23:45 | Club Nacional Asunción | | - | | Deportivo Táchira | 3 | : | 2 |
| Group A |
Mar 14 • 02:00 | SC Internacional | | - | | The Strongest | 5 | : | 0 |
| Group E |
Mar 14 • 02:00 | Alianza Lima | | - | | Club Nacional Montevideo | 1 | : | 0 |
| Group G |
Mar 14 • 04:15 | Chivas Guadalajara | | - | | Defensor Sporting | 1 | : | 0 |
| Group D |
Mar 14 • 23:45 | Arsenal de Sarandí | | - | | Boca Juniors | 1 | : | 2 |
| Group D |
Mar 14 • 23:45 | Fluminense FC | | - | | Zamora FC | 1 | : | 0 |
| Group E |
Mar 15 • 02:00 | Club Libertad | | - | | CR Vasco da Gama | 1 | : | 1 |
| Group F |
Mar 15 • 02:00 | Cruz Azul | | - | | Corinthians | 0 | : | 0 |
| Group A |
Mar 15 • 23:45 | Juan Aurich | | - | | Santos FC | 1 | : | 3 |
| Group B |
Mar 16 • 02:00 | Flamengo | | - | | Olimpia Asunción | 3 | : | 3 |
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| Group B |
Mar 21 • 00:15 | CS Emelec | | - | | CA Lanús | 0 | : | 2 |
| Group C |
Mar 21 • 02:30 | Club Bolívar | | - | | Atlético Junior | 2 | : | 1 |
| Group A |
Mar 21 • 23:45 | The Strongest | | - | | SC Internacional | 1 | : | 1 |
| Group E |
Mar 22 • 02:00 | CR Vasco da Gama | | - | | Club Libertad | 2 | : | 0 |
| Group F |
Mar 22 • 02:00 | Corinthians | | - | | Cruz Azul | 1 | : | 0 |
| Group G |
Mar 22 • 23:45 | Vélez Sársfield | | - | | Deportivo Quito | 1 | : | 0 |
| Group A |
Mar 23 • 02:00 | Santos FC | | - | | Juan Aurich | 2 | : | 0 |
| Group H |
Mar 23 • 02:00 | Atlético Nacional | | - | | Godoy Cruz | 2 | : | 2 |
| Group E |
Mar 28 • 00:15 | Club Nacional Montevideo | | - | | Alianza Lima | 1 | : | 0 |
| Group F |
Mar 28 • 02:30 | Deportivo Táchira | | - | | Club Nacional Asunción | 0 | : | 0 |
| Group H |
Mar 28 • 02:30 | Universidad de Chile | | - | | CA Peñarol | 2 | : | 1 |
| Group C |
Mar 29 • 00:45 | CD Universidad Católica | | - | | Unión Española | 2 | : | 1 |
| Group G |
Mar 29 • 00:45 | Defensor Sporting | | - | | Chivas Guadalajara | 1 | : | 0 |
| Group B |
Mar 29 • 03:00 | Olimpia Asunción | | - | | Flamengo | 3 | : | 2 |
| Group D |
Mar 30 • 00:45 | Boca Juniors | | - | | Arsenal de Sarandí | 2 | : | 0 |
| Group D |
Mar 30 • 03:00 | Zamora FC | | - | | Fluminense FC | 0 | : | 1 |
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| Group B |
Apr 04 • 00:45 | CA Lanús | | - | | Olimpia Asunción | 6 | : | 0 |
| Group E |
Apr 04 • 03:00 | Alianza Lima | | - | | CR Vasco da Gama | 1 | : | 2 |
| Group F |
Apr 04 • 03:00 | Deportivo Táchira | | - | | Cruz Azul | 1 | : | 1 |
| Group H |
Apr 05 • 00:30 | Godoy Cruz | | - | | Universidad de Chile | 0 | : | 1 |
| Group A |
Apr 05 • 02:50 | SC Internacional | | - | | Santos FC | 1 | : | 1 |
| Group B |
Apr 05 • 02:50 | CS Emelec | | - | | Flamengo | 3 | : | 2 |
| Group C |
Apr 05 • 02:50 | Atlético Junior | | - | | CD Universidad Católica | 3 | : | 0 |
| Group E |
Apr 06 • 01:15 | Club Libertad | | - | | Club Nacional Montevideo | 2 | : | 1 |
| Group A |
Apr 06 • 03:30 | Juan Aurich | | - | | The Strongest | 1 | : | 0 |
| Group G |
Apr 10 • 23:30 | Deportivo Quito | | - | | Defensor Sporting | 2 | : | 0 |
| Group C |
Apr 11 • 01:45 | Unión Española | | - | | Club Bolívar | 2 | : | 1 |
| Group D |
Apr 11 • 01:45 | Zamora FC | | - | | Arsenal de Sarandí | 0 | : | 1 |
| Group H |
Apr 11 • 04:00 | Atlético Nacional | | - | | CA Peñarol | 3 | : | 0 |
| Group G |
Apr 12 • 00:45 | Chivas Guadalajara | | - | | Vélez Sársfield | 0 | : | 2 |
| Group D |
Apr 12 • 03:00 | Fluminense FC | | - | | Boca Juniors | 0 | : | 2 |
| Group F |
Apr 12 • 03:00 | Club Nacional Asunción | | - | | Corinthians | 1 | : | 3 |
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| Group B |
Apr 13 • 00:30 | Flamengo | | - | | CA Lanús | 3 | : | 0 |
| Group B |
Apr 13 • 00:30 | Olimpia Asunción | | - | | CS Emelec | 2 | : | 3 |
| Group E |
Apr 13 • 02:50 | Alianza Lima | | - | | Club Libertad | 1 | : | 2 |
| Group E |
Apr 13 • 02:50 | Club Nacional Montevideo | | - | | CR Vasco da Gama | 0 | : | 1 |
| Group G |
Apr 18 • 01:15 | Deportivo Quito | | - | | Chivas Guadalajara | 5 | : | 0 |
| Group G |
Apr 18 • 01:15 | Vélez Sársfield | | - | | Defensor Sporting | 1 | : | 3 |
| Group C |
Apr 18 • 03:30 | Atlético Junior | | - | | Unión Española | 2 | : | 1 |
| Group C |
Apr 18 • 03:30 | Club Bolívar | | - | | CD Universidad Católica | 3 | : | 0 |
| Group D |
Apr 19 • 00:30 | Boca Juniors | | - | | Zamora FC | 2 | : | 0 |
| Group D |
Apr 19 • 00:30 | Arsenal de Sarandí | | - | | Fluminense FC | 1 | : | 2 |
| Group F |
Apr 19 • 02:50 | Cruz Azul | | - | | Club Nacional Asunción | 4 | : | 1 |
| Group F |
Apr 19 • 02:50 | Corinthians | | - | | Deportivo Táchira | 6 | : | 0 |
| Group A |
Apr 20 • 00:45 | Juan Aurich | | - | | SC Internacional | 1 | : | 0 |
| Group A |
Apr 20 • 00:45 | Santos FC | | - | | The Strongest | 2 | : | 0 |
| Group H |
Apr 20 • 03:00 | CA Peñarol | | - | | Godoy Cruz | 4 | : | 2 |
| Group H |
Apr 20 • 03:00 | Universidad de Chile | | - | | Atlético Nacional | 2 | : | 1 |
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| Apr 26 • 02:50 | SC Internacional | | - | | Fluminense FC | 0 | : | 0 |
| Apr 26 • 02:50 | Club Bolívar | | - | | Santos FC | 2 | : | 1 |
| May 02 • 02:15 | Atlético Nacional | | - | | Vélez Sársfield | 0 | : | 1 |
| May 02 • 04:30 | Cruz Azul | | - | | Club Libertad | 1 | : | 1 |
| May 03 • 00:30 | Boca Juniors | | - | | Unión Española | 2 | : | 1 |
| May 03 • 02:50 | CR Vasco da Gama | | - | | CA Lanús | 2 | : | 1 |
| May 03 • 02:50 | CS Emelec | | - | | Corinthians | 0 | : | 0 |
| May 04 • 02:15 | Deportivo Quito | | - | | Universidad de Chile | 4 | : | 1 |
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| May 09 • 01:00 | Vélez Sársfield | | - | | Atlético Nacional | 1 | : | 1 |
| May 09 • 03:30 | Club Libertad | | - | | Cruz Azul | 2 | : | 0 |
| May 10 • 00:30 | Unión Española | | - | | Boca Juniors | 2 | : | 3 |
| May 10 • 03:00 | CA Lanús | | - | | CR Vasco da Gama | 6 | : | 6 |
| May 10 • 03:00 | Corinthians | | - | | CS Emelec | 3 | : | 0 |
| May 11 • 00:30 | Santos FC | | - | | Club Bolívar | 8 | : | 0 |
| May 11 • 03:00 | Fluminense FC | | - | | SC Internacional | 2 | : | 1 |
| May 11 • 03:00 | Universidad de Chile | | - | | Deportivo Quito | 6 | : | 0 |
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| May 17 • 00:30 | Club Libertad | | - | | Universidad de Chile | 1 | : | 1 |
| May 17 • 02:50 | CR Vasco da Gama | | - | | Corinthians | 0 | : | 0 |
| May 18 • 00:45 | Boca Juniors | | - | | Fluminense FC | 1 | : | 0 |
| May 18 • 03:00 | Vélez Sársfield | | - | | Santos FC | 1 | : | 0 |
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| May 24 • 00:30 | Fluminense FC | | - | | Boca Juniors | 1 | : | 1 |
| May 24 • 03:00 | Corinthians | | - | | CR Vasco da Gama | 1 | : | 0 |
| May 25 • 01:00 | Santos FC | | - | | Vélez Sársfield | 5 | : | 2 |
| May 25 • 03:30 | Universidad de Chile | | - | | Club Libertad | 6 | : | 4 |
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| Jun 14 • 02:50 | Santos FC | | - | | Corinthians | 0 | : | 1 |
| Jun 15 • 01:15 | Boca Juniors | | - | | Universidad de Chile | 2 | : | 0 |
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| Jun 21 • 02:50 | Corinthians | | - | | Santos FC | 1 | : | 1 |
| Jun 22 • 02:15 | Universidad de Chile | | - | | Boca Juniors | 0 | : | 0 |
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| Jun 28 • 02:50 | Boca Juniors | | - | | Corinthians | 1 | : | 1 |
| Jul 05 • 02:50 | Corinthians | | - | | Boca Juniors | 2 | : | 0 |
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