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| Feb 04 • 01:15 | Alianza Lima |  | - |  | CA Huracán | 0 | : | 4 |
| Feb 04 • 03:30 | Monarcas Morelia |  | - |  | The Strongest | 1 | : | 1 |
| Feb 05 • 01:00 | Corinthians |  | - |  | Once Caldas | 4 | : | 0 |
| Feb 05 • 03:15 | Deportivo Táchira |  | - |  | Cerro Porteño | 2 | : | 1 |
| Feb 05 • 23:45 | CD Palestino |  | - |  | Club Nacional Montevideo | 1 | : | 0 |
| Feb 06 • 02:00 | Independiente del Valle |  | - |  | Estudiantes de La Plata | 1 | : | 0 |
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| Feb 10 • 23:15 | CA Huracán | | - | | Alianza Lima | 0 | : | 0 |
| Feb 11 • 01:45 | The Strongest | | - | | Monarcas Morelia | 2 | : | 0 |
| Feb 11 • 22:30 | Cerro Porteño | | - | | Deportivo Táchira | 2 | : | 2 |
| Feb 12 • 01:00 | Once Caldas | | - | | Corinthians | 1 | : | 1 |
| Feb 12 • 23:15 | Club Nacional Montevideo | | - | | CD Palestino | 2 | : | 1 |
| Feb 13 • 01:45 | Estudiantes de La Plata | | - | | Independiente del Valle | 4 | : | 0 |
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| Group D |
Feb 17 • 23:15 | Universidad de Chile |  | - |  | CS Emelec | 0 | : | 1 |
| Group E |
Feb 17 • 23:15 | Montevideo Wanderers |  | - |  | Zamora FC | 3 | : | 2 |
| Group D |
Feb 18 • 01:30 | The Strongest | | - |  | SC Internacional | 3 | : | 1 |
| Group H |
Feb 18 • 01:30 | Deportivo Táchira | | - |  | Racing Club | 0 | : | 5 |
| Group A |
Feb 18 • 03:45 | CF Atlas |  | - |  | Independiente Santa Fe | 0 | : | 1 |
| Group E |
Feb 18 • 22:45 | CD Palestino | | - |  | Boca Juniors | 0 | : | 2 |
| Group H |
Feb 18 • 22:45 | Club Guaraní |  | - |  | Sporting Cristal | 2 | : | 2 |
| Group A |
Feb 19 • 01:00 | Colo-Colo |  | - |  | Atlético Mineiro | 2 | : | 0 |
| Group B |
Feb 19 • 01:00 | Corinthians | | - |  | São Paulo FC | 2 | : | 0 |
| Group F |
Feb 19 • 03:15 | UANL Tigres |  | - |  | Juan Aurich | 3 | : | 0 |
| Group B |
Feb 19 • 23:45 | Danubio FC |  | - |  | San Lorenzo | 1 | : | 2 |
| Group G |
Feb 19 • 23:45 | Club Libertad |  | - |  | Atlético Nacional | 2 | : | 2 |
| Group F |
Feb 20 • 02:00 | Club San José |  | - |  | River Plate | 2 | : | 0 |
| Group C |
Feb 24 • 23:00 | CA Huracán | | - |  | Mineros de Guayana | 2 | : | 2 |
| Group G |
Feb 25 • 23:45 | Estudiantes de La Plata | | - |  | Barcelona SC | 3 | : | 0 |
| Group C |
Feb 26 • 02:00 | Club Universitario de Sucre |  | - |  | Cruzeiro EC | 0 | : | 0 |
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| Group H |
Feb 25 • 01:15 | Racing Club | | - | | Club Guaraní | 4 | : | 1 |
| Group D |
Feb 25 • 03:30 | CS Emelec | | - | | The Strongest | 3 | : | 0 |
| Group H |
Feb 25 • 03:30 | Sporting Cristal | | - | | Deportivo Táchira | 1 | : | 1 |
| Group A |
Feb 25 • 23:45 | Atlético Mineiro | | - | | CF Atlas | 0 | : | 1 |
| Group B |
Feb 26 • 02:00 | São Paulo FC | | - | | Danubio FC | 4 | : | 0 |
| Group D |
Feb 27 • 00:15 | SC Internacional | | - | | Universidad de Chile | 3 | : | 1 |
| Group E |
Feb 27 • 00:15 | Boca Juniors | | - | | Montevideo Wanderers | 2 | : | 1 |
| Group A |
Feb 27 • 02:30 | Independiente Santa Fe | | - | | Colo-Colo | 3 | : | 1 |
| Group E |
Feb 27 • 02:30 | Zamora FC | | - | | CD Palestino | 0 | : | 1 |
| Group C |
Mar 03 • 23:45 | Mineros de Guayana | | - | | Club Universitario de Sucre | 0 | : | 1 |
| Group G |
Mar 03 • 23:45 | Barcelona SC | | - | | Club Libertad | 0 | : | 1 |
| Group C |
Mar 04 • 02:00 | Cruzeiro EC | | - | | CA Huracán | 0 | : | 0 |
| Group B |
Mar 05 • 02:00 | San Lorenzo | | - | | Corinthians | 0 | : | 1 |
| Group F |
Mar 06 • 00:15 | River Plate | | - | | UANL Tigres | 1 | : | 1 |
| Group F |
Mar 06 • 02:30 | Juan Aurich | | - | | Club San José | 2 | : | 0 |
| Group G |
Mar 06 • 02:30 | Atlético Nacional | | - | | Estudiantes de La Plata | 1 | : | 1 |
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| Group A |
Mar 04 • 23:45 | Colo-Colo | | - | | CF Atlas | 2 | : | 0 |
| Group D |
Mar 05 • 02:00 | SC Internacional | | - | | CS Emelec | 3 | : | 2 |
| Group D |
Mar 06 • 00:15 | Universidad de Chile | | - | | The Strongest | 3 | : | 1 |
| Group C |
Mar 10 • 23:30 | Club Universitario de Sucre | | - | | CA Huracán | 0 | : | 0 |
| Group E |
Mar 10 • 23:30 | Montevideo Wanderers | | - | | CD Palestino | 1 | : | 0 |
| Group H |
Mar 11 • 01:45 | Racing Club | | - | | Sporting Cristal | 1 | : | 2 |
| Group H |
Mar 11 • 01:45 | Club Guaraní | | - | | Deportivo Táchira | 5 | : | 2 |
| Group E |
Mar 12 • 00:00 | Boca Juniors | | - | | Zamora FC | 5 | : | 0 |
| Group F |
Mar 12 • 02:15 | Club San José | | - | | UANL Tigres | 0 | : | 1 |
| Group G |
Mar 12 • 02:15 | Barcelona SC | | - | | Atlético Nacional | 1 | : | 2 |
| Group G |
Mar 12 • 23:45 | Club Libertad | | - | | Estudiantes de La Plata | 1 | : | 0 |
| Group F |
Mar 13 • 02:15 | Juan Aurich | | - | | River Plate | 1 | : | 1 |
| Group B |
Mar 18 • 00:00 | Danubio FC | | - | | Corinthians | 1 | : | 2 |
| Group A |
Mar 19 • 02:00 | Independiente Santa Fe | | - | | Atlético Mineiro | 0 | : | 1 |
| Group B |
Mar 19 • 02:00 | São Paulo FC | | - | | San Lorenzo | 1 | : | 0 |
| Group C |
Mar 20 • 02:15 | Mineros de Guayana | | - | | Cruzeiro EC | 0 | : | 2 |
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| Group H |
Mar 18 • 00:00 | Sporting Cristal | | - | | Racing Club | 0 | : | 2 |
| Group D |
Mar 18 • 02:15 | The Strongest | | - | | Universidad de Chile | 5 | : | 3 |
| Group E |
Mar 18 • 02:15 | Zamora FC | | - | | Boca Juniors | 1 | : | 5 |
| Group F |
Mar 18 • 04:30 | UANL Tigres | | - | | Club San José | 4 | : | 0 |
| Group D |
Mar 18 • 23:45 | CS Emelec | | - | | SC Internacional | 1 | : | 1 |
| Group G |
Mar 18 • 23:45 | Estudiantes de La Plata | | - | | Club Libertad | 1 | : | 0 |
| Group H |
Mar 19 • 02:00 | Deportivo Táchira | | - | | Club Guaraní | 1 | : | 1 |
| Group E |
Mar 20 • 00:00 | CD Palestino | | - | | Montevideo Wanderers | 1 | : | 1 |
| Group F |
Mar 20 • 00:00 | River Plate | | - | | Juan Aurich | 1 | : | 1 |
| Group G |
Mar 20 • 02:15 | Atlético Nacional | | - | | Barcelona SC | 2 | : | 3 |
| Group B |
Apr 02 • 00:45 | San Lorenzo | | - | | São Paulo FC | 1 | : | 0 |
| Group B |
Apr 02 • 03:00 | Corinthians | | - | | Danubio FC | 4 | : | 0 |
| Group A |
Apr 08 • 03:15 | CF Atlas | | - | | Colo-Colo | 1 | : | 3 |
| Group C |
Apr 09 • 00:45 | CA Huracán | | - | | Club Universitario de Sucre | 1 | : | 1 |
| Group C |
Apr 09 • 03:00 | Cruzeiro EC | | - | | Mineros de Guayana | 3 | : | 0 |
| Group A |
Apr 10 • 02:45 | Atlético Mineiro | | - | | Independiente Santa Fe | 2 | : | 0 |
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| Group E |
Apr 08 • 01:00 | CD Palestino | | - | | Zamora FC | 4 | : | 0 |
| Group H |
Apr 08 • 01:00 | Club Guaraní | | - | | Racing Club | 2 | : | 0 |
| Group F |
Apr 08 • 03:15 | Club San José | | - | | Juan Aurich | 1 | : | 1 |
| Group H |
Apr 09 • 00:45 | Deportivo Táchira | | - | | Sporting Cristal | 0 | : | 0 |
| Group F |
Apr 09 • 03:00 | UANL Tigres | | - | | River Plate | 2 | : | 2 |
| Group G |
Apr 10 • 00:30 | Estudiantes de La Plata | | - | | Atlético Nacional | 0 | : | 1 |
| Group G |
Apr 10 • 00:30 | Club Libertad | | - | | Barcelona SC | 1 | : | 1 |
| Group E |
Apr 10 • 02:45 | Montevideo Wanderers | | - | | Boca Juniors | 0 | : | 3 |
| Group C |
Apr 15 • 00:00 | CA Huracán | | - | | Cruzeiro EC | 3 | : | 1 |
| Group C |
Apr 15 • 00:00 | Club Universitario de Sucre | | - | | Mineros de Guayana | 2 | : | 0 |
| Group D |
Apr 15 • 22:30 | The Strongest | | - | | CS Emelec | 1 | : | 0 |
| Group A |
Apr 16 • 03:00 | CF Atlas | | - | | Atlético Mineiro | 1 | : | 0 |
| Group A |
Apr 16 • 03:00 | Colo-Colo | | - | | Independiente Santa Fe | 0 | : | 3 |
| Group B |
Apr 16 • 03:00 | Danubio FC | | - | | São Paulo FC | 1 | : | 2 |
| Group B |
Apr 17 • 03:00 | Corinthians | | - | | San Lorenzo | 0 | : | 0 |
| Group D |
Apr 17 • 03:00 | Universidad de Chile | | - | | SC Internacional | 0 | : | 4 |
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| Group H |
Apr 15 • 02:15 | Sporting Cristal | | - | | Club Guaraní | 1 | : | 1 |
| Group H |
Apr 15 • 02:15 | Racing Club | | - | | Deportivo Táchira | 3 | : | 2 |
| Group F |
Apr 16 • 00:45 | River Plate | | - | | Club San José | 3 | : | 0 |
| Group F |
Apr 16 • 00:45 | Juan Aurich | | - | | UANL Tigres | 4 | : | 5 |
| Group E |
Apr 17 • 00:45 | Zamora FC | | - | | Montevideo Wanderers | 0 | : | 3 |
| Group E |
Apr 17 • 00:45 | Boca Juniors | | - | | CD Palestino | 2 | : | 0 |
| Group C |
Apr 22 • 01:30 | Cruzeiro EC | | - | | Club Universitario de Sucre | 2 | : | 0 |
| Group C |
Apr 22 • 01:30 | Mineros de Guayana | | - | | CA Huracán | 3 | : | 0 |
| Group G |
Apr 22 • 03:45 | Atlético Nacional | | - | | Club Libertad | 4 | : | 0 |
| Group G |
Apr 22 • 03:45 | Barcelona SC | | - | | Estudiantes de La Plata | 0 | : | 2 |
| Group D |
Apr 22 • 22:30 | CS Emelec | | - | | Universidad de Chile | 2 | : | 0 |
| Group D |
Apr 22 • 22:30 | SC Internacional | | - | | The Strongest | 1 | : | 0 |
| Group A |
Apr 23 • 00:45 | Atlético Mineiro | | - | | Colo-Colo | 2 | : | 0 |
| Group A |
Apr 23 • 00:45 | Independiente Santa Fe | | - | | CF Atlas | 3 | : | 1 |
| Group B |
Apr 23 • 03:00 | San Lorenzo | | - | | Danubio FC | 0 | : | 1 |
| Group B |
Apr 23 • 03:00 | São Paulo FC | | - | | Corinthians | 2 | : | 0 |
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| Apr 29 • 02:30 | Club Universitario de Sucre | | - | | UANL Tigres | 1 | : | 2 |
| May 06 • 01:45 | Estudiantes de La Plata | | - | | Independiente Santa Fe | 2 | : | 1 |
| May 07 • 00:45 | Club Guaraní | | - | | Corinthians | 2 | : | 0 |
| May 07 • 03:00 | São Paulo FC | | - | | Cruzeiro EC | 1 | : | 0 |
| May 07 • 03:00 | Atlético Mineiro | | - | | SC Internacional | 2 | : | 2 |
| May 07 • 23:45 | Montevideo Wanderers | | - | | Racing Club | 1 | : | 1 |
| May 08 • 02:00 | River Plate | | - | | Boca Juniors | 1 | : | 0 |
| May 08 • 04:15 | CS Emelec | | - | | Atlético Nacional | 2 | : | 0 |
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| May 06 • 04:00 | UANL Tigres | | - | | Club Universitario de Sucre | 1 | : | 1 |
| May 13 • 02:30 | Independiente Santa Fe | | - | | Estudiantes de La Plata | 2 | : | 0 |
| May 14 • 00:30 | Cruzeiro EC | | - | | São Paulo FC | 1 | : | 0 |
| May 14 • 03:00 | Corinthians | | - | | Club Guaraní | 0 | : | 1 |
| May 14 • 03:00 | SC Internacional | | - | | Atlético Mineiro | 3 | : | 1 |
| May 14 • 23:30 | Racing Club | | - | | Montevideo Wanderers | 2 | : | 1 |
| May 15 • 02:00 | Boca Juniors | | - | | River Plate | 0 | : | 3 |
| May 15 • 04:30 | Atlético Nacional | | - | | CS Emelec | 1 | : | 0 |
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| May 20 • 03:00 | CS Emelec | | - | | UANL Tigres | 1 | : | 0 |
| May 21 • 03:00 | Independiente Santa Fe | | - | | SC Internacional | 1 | : | 0 |
| May 22 • 00:45 | Club Guaraní | | - | | Racing Club | 1 | : | 0 |
| May 22 • 03:00 | River Plate | | - | | Cruzeiro EC | 0 | : | 1 |
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| May 27 • 03:00 | UANL Tigres | | - | | CS Emelec | 2 | : | 0 |
| May 28 • 00:30 | SC Internacional | | - | | Independiente Santa Fe | 2 | : | 0 |
| May 28 • 03:00 | Cruzeiro EC | | - | | River Plate | 0 | : | 3 |
| May 29 • 02:00 | Racing Club | | - | | Club Guaraní | 0 | : | 0 |
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| Jul 15 • 02:00 | River Plate | | - | | Club Guaraní | 2 | : | 0 |
| Jul 16 • 03:00 | SC Internacional | | - | | UANL Tigres | 2 | : | 1 |
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| Jul 22 • 02:00 | Club Guaraní | | - | | River Plate | 1 | : | 1 |
| Jul 23 • 03:00 | UANL Tigres | | - | | SC Internacional | 3 | : | 1 |
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| Jul 30 • 03:00 | UANL Tigres | | - | | River Plate | 0 | : | 0 |
| Aug 06 • 03:00 | River Plate | | - | | UANL Tigres | 3 | : | 0 |
