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|
| Aug 24 • 19:00 | Slavia Prague |  | - |  | Zorya Luhansk | 2 | : | 0 |
| Aug 24 • 19:00 | BK Häcken |  | - |  | Aberdeen FC | 2 | : | 2 |
| Aug 24 • 20:00 | Ludogorets Razgrad |  | - |  | Ajax Amsterdam | 1 | : | 4 |
| Aug 24 • 20:00 | Olimpija Ljubljana |  | - |  | Qarabağ FK | 0 | : | 2 |
| Aug 24 • 20:00 | Dinamo Zagreb |  | - |  | Sparta Prague | 3 | : | 1 |
| Aug 24 • 20:30 | Royale Union Saint-Gilloise |  | - |  | FC Lugano | 2 | : | 0 |
| Aug 24 • 20:30 | Slovan Bratislava |  | - |  | Aris Limassol | 2 | : | 1 |
| Aug 24 • 20:45 | KÍ Klaksvík |  | - |  | Sheriff Tiraspol | 1 | : | 1 |
| Aug 24 • 21:00 | Olympiacos CFP |  | - |  | FK Čukarički | 3 | : | 1 |
| Aug 24 • 21:00 | LASK |  | - |  | HŠK Zrinjski Mostar | 2 | : | 1 |
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| Aug 31 • 18:00 | Qarabağ FK | | - | | Olimpija Ljubljana | 1 | : | 1 |
| Aug 31 • 19:00 | Zorya Luhansk | | - | | Slavia Prague | 2 | : | 1 |
| Aug 31 • 19:00 | Sheriff Tiraspol | | - | | KÍ Klaksvík | 2 | : | 1 |
| Aug 31 • 19:00 | Aris Limassol | | - | | Slovan Bratislava | 6 | : | 2 |
| Aug 31 • 19:00 | Sparta Prague | | - | | Dinamo Zagreb | 4 | : | 1 |
| Aug 31 • 20:00 | FK Čukarički | | - | | Olympiacos CFP | 0 | : | 3 |
| Aug 31 • 20:00 | Ajax Amsterdam | | - | | Ludogorets Razgrad | 0 | : | 1 |
| Aug 31 • 20:30 | FC Lugano | | - | | Royale Union Saint-Gilloise | 0 | : | 1 |
| Aug 31 • 20:45 | Aberdeen FC | | - | | BK Häcken | 1 | : | 3 |
| Aug 31 • 21:00 | HŠK Zrinjski Mostar | | - | | LASK | 1 | : | 1 |
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| Group E |
Sep 21 • 18:45 | LASK | | - |  | Liverpool FC | 1 | : | 3 |
| Group E |
Sep 21 • 18:45 | Royale Union Saint-Gilloise | | - |  | Toulouse FC | 1 | : | 1 |
| Group F |
Sep 21 • 18:45 | Stade Rennes |  | - |  | Maccabi Haifa | 3 | : | 0 |
| Group F |
Sep 21 • 18:45 | Panathinaikos FC |  | - |  | Villarreal CF | 2 | : | 0 |
| Group G |
Sep 21 • 18:45 | Sheriff Tiraspol | | - |  | AS Roma | 1 | : | 2 |
| Group G |
Sep 21 • 18:45 | Servette FC |  | - | | Slavia Prague | 0 | : | 2 |
| Group H |
Sep 21 • 18:45 | Bayer Leverkusen |  | - | | BK Häcken | 4 | : | 0 |
| Group H |
Sep 21 • 18:45 | Qarabağ FK | | - |  | Molde FK | 1 | : | 0 |
| Group A |
Sep 21 • 21:00 | West Ham United |  | - |  | FK TSC Bačka Topola | 3 | : | 1 |
| Group A |
Sep 21 • 21:00 | Olympiacos CFP | | - |  | SC Freiburg | 2 | : | 3 |
| Group B |
Sep 21 • 21:00 | Ajax Amsterdam | | - |  | Olympique Marseille | 3 | : | 3 |
| Group B |
Sep 21 • 21:00 | Brighton & Hove Albion |  | - |  | AEK Athens | 2 | : | 3 |
| Group C |
Sep 21 • 21:00 | Rangers FC |  | - |  | Real Betis | 1 | : | 0 |
| Group C |
Sep 21 • 21:00 | Sparta Prague | | - | | Aris Limassol | 3 | : | 2 |
| Group D |
Sep 21 • 21:00 | Atalanta BC |  | - |  | Raków Częstochowa | 2 | : | 0 |
| Group D |
Sep 21 • 21:00 | Sturm Graz |  | - |  | Sporting CP | 1 | : | 2 |
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| Group A |
Oct 05 • 18:45 | SC Freiburg | | - | | West Ham United | 1 | : | 2 |
| Group A |
Oct 05 • 18:45 | FK TSC Bačka Topola | | - | | Olympiacos CFP | 2 | : | 2 |
| Group B |
Oct 05 • 18:45 | Olympique Marseille | | - | | Brighton & Hove Albion | 2 | : | 2 |
| Group B |
Oct 05 • 18:45 | AEK Athens | | - | | Ajax Amsterdam | 1 | : | 1 |
| Group C |
Oct 05 • 18:45 | Real Betis | | - | | Sparta Prague | 2 | : | 1 |
| Group C |
Oct 05 • 18:45 | Aris Limassol | | - | | Rangers FC | 2 | : | 1 |
| Group D |
Oct 05 • 18:45 | Sporting CP | | - | | Atalanta BC | 1 | : | 2 |
| Group D |
Oct 05 • 18:45 | Raków Częstochowa | | - | | Sturm Graz | 0 | : | 1 |
| Group E |
Oct 05 • 21:00 | Liverpool FC | | - | | Royale Union Saint-Gilloise | 2 | : | 0 |
| Group E |
Oct 05 • 21:00 | Toulouse FC | | - | | LASK | 1 | : | 0 |
| Group F |
Oct 05 • 21:00 | Villarreal CF | | - | | Stade Rennes | 1 | : | 0 |
| Group F |
Oct 05 • 21:00 | Maccabi Haifa | | - | | Panathinaikos FC | 0 | : | 0 |
| Group G |
Oct 05 • 21:00 | AS Roma | | - | | Servette FC | 4 | : | 0 |
| Group G |
Oct 05 • 21:00 | Slavia Prague | | - | | Sheriff Tiraspol | 6 | : | 0 |
| Group H |
Oct 05 • 21:00 | Molde FK | | - | | Bayer Leverkusen | 1 | : | 2 |
| Group H |
Oct 05 • 21:00 | BK Häcken | | - | | Qarabağ FK | 0 | : | 1 |
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|
|
| Group A |
Oct 26 • 18:45 | Olympiacos CFP | | - | | West Ham United | 2 | : | 1 |
| Group A |
Oct 26 • 18:45 | FK TSC Bačka Topola | | - | | SC Freiburg | 1 | : | 3 |
| Group B |
Oct 26 • 18:45 | Olympique Marseille | | - | | AEK Athens | 3 | : | 1 |
| Group C |
Oct 26 • 18:45 | Sparta Prague | | - | | Rangers FC | 0 | : | 0 |
| Group C |
Oct 26 • 18:45 | Aris Limassol | | - | | Real Betis | 0 | : | 1 |
| Group D |
Oct 26 • 18:45 | Sturm Graz | | - | | Atalanta BC | 2 | : | 2 |
| Group D |
Oct 26 • 18:45 | Raków Częstochowa | | - | | Sporting CP | 1 | : | 1 |
| Group H |
Oct 26 • 18:45 | Molde FK | | - | | BK Häcken | 5 | : | 1 |
| Group B |
Oct 26 • 21:00 | Brighton & Hove Albion | | - | | Ajax Amsterdam | 2 | : | 0 |
| Group E |
Oct 26 • 21:00 | Liverpool FC | | - | | Toulouse FC | 5 | : | 1 |
| Group E |
Oct 26 • 21:00 | Royale Union Saint-Gilloise | | - | | LASK | 2 | : | 1 |
| Group F |
Oct 26 • 21:00 | Panathinaikos FC | | - | | Stade Rennes | 1 | : | 2 |
| Group G |
Oct 26 • 21:00 | AS Roma | | - | | Slavia Prague | 2 | : | 0 |
| Group G |
Oct 26 • 21:00 | Sheriff Tiraspol | | - | | Servette FC | 1 | : | 1 |
| Group H |
Oct 26 • 21:00 | Bayer Leverkusen | | - | | Qarabağ FK | 5 | : | 1 |
| Group F |
Dec 06 • 21:00 | Villarreal CF | | - | | Maccabi Haifa | 0 | : | 0 |
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| Group B |
Nov 09 • 18:45 | Ajax Amsterdam | | - | | Brighton & Hove Albion | 0 | : | 2 |
| Group E |
Nov 09 • 18:45 | LASK | | - | | Royale Union Saint-Gilloise | 3 | : | 0 |
| Group E |
Nov 09 • 18:45 | Toulouse FC | | - | | Liverpool FC | 3 | : | 2 |
| Group F |
Nov 09 • 18:45 | Stade Rennes | | - | | Panathinaikos FC | 3 | : | 1 |
| Group F |
Nov 09 • 18:45 | Maccabi Haifa | | - | | Villarreal CF | 1 | : | 2 |
| Group G |
Nov 09 • 18:45 | Slavia Prague | | - | | AS Roma | 2 | : | 0 |
| Group G |
Nov 09 • 18:45 | Servette FC | | - | | Sheriff Tiraspol | 2 | : | 1 |
| Group H |
Nov 09 • 18:45 | Qarabağ FK | | - | | Bayer Leverkusen | 0 | : | 1 |
| Group A |
Nov 09 • 21:00 | West Ham United | | - | | Olympiacos CFP | 1 | : | 0 |
| Group A |
Nov 09 • 21:00 | SC Freiburg | | - | | FK TSC Bačka Topola | 5 | : | 0 |
| Group B |
Nov 09 • 21:00 | AEK Athens | | - | | Olympique Marseille | 0 | : | 2 |
| Group C |
Nov 09 • 21:00 | Rangers FC | | - | | Sparta Prague | 2 | : | 1 |
| Group C |
Nov 09 • 21:00 | Real Betis | | - | | Aris Limassol | 4 | : | 1 |
| Group D |
Nov 09 • 21:00 | Atalanta BC | | - | | Sturm Graz | 1 | : | 0 |
| Group D |
Nov 09 • 21:00 | Sporting CP | | - | | Raków Częstochowa | 2 | : | 1 |
| Group H |
Nov 09 • 21:00 | BK Häcken | | - | | Molde FK | 1 | : | 3 |
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| Group A |
Nov 30 • 18:45 | SC Freiburg | | - | | Olympiacos CFP | 5 | : | 0 |
| Group A |
Nov 30 • 18:45 | FK TSC Bačka Topola | | - | | West Ham United | 0 | : | 1 |
| Group B |
Nov 30 • 18:45 | AEK Athens | | - | | Brighton & Hove Albion | 0 | : | 1 |
| Group C |
Nov 30 • 18:45 | Sparta Prague | | - | | Real Betis | 1 | : | 0 |
| Group D |
Nov 30 • 18:45 | Atalanta BC | | - | | Sporting CP | 1 | : | 1 |
| Group D |
Nov 30 • 18:45 | Sturm Graz | | - | | Raków Częstochowa | 0 | : | 1 |
| Group F |
Nov 30 • 18:45 | Maccabi Haifa | | - | | Stade Rennes | 0 | : | 3 |
| Group B |
Nov 30 • 21:00 | Olympique Marseille | | - | | Ajax Amsterdam | 4 | : | 3 |
| Group C |
Nov 30 • 21:00 | Rangers FC | | - | | Aris Limassol | 1 | : | 1 |
| Group E |
Nov 30 • 21:00 | Liverpool FC | | - | | LASK | 4 | : | 0 |
| Group E |
Nov 30 • 21:00 | Toulouse FC | | - | | Royale Union Saint-Gilloise | 0 | : | 0 |
| Group F |
Nov 30 • 21:00 | Villarreal CF | | - | | Panathinaikos FC | 3 | : | 2 |
| Group G |
Nov 30 • 21:00 | Sheriff Tiraspol | | - | | Slavia Prague | 2 | : | 3 |
| Group G |
Nov 30 • 21:00 | Servette FC | | - | | AS Roma | 1 | : | 1 |
| Group H |
Nov 30 • 21:00 | Molde FK | | - | | Qarabağ FK | 2 | : | 2 |
| Group H |
Nov 30 • 21:00 | BK Häcken | | - | | Bayer Leverkusen | 0 | : | 2 |
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| Group E |
Dec 14 • 18:45 | LASK | | - | | Toulouse FC | 1 | : | 2 |
| Group E |
Dec 14 • 18:45 | Royale Union Saint-Gilloise | | - | | Liverpool FC | 2 | : | 1 |
| Group F |
Dec 14 • 18:45 | Stade Rennes | | - | | Villarreal CF | 2 | : | 3 |
| Group F |
Dec 14 • 18:45 | Panathinaikos FC | | - | | Maccabi Haifa | 1 | : | 2 |
| Group G |
Dec 14 • 18:45 | AS Roma | | - | | Sheriff Tiraspol | 3 | : | 0 |
| Group G |
Dec 14 • 18:45 | Slavia Prague | | - | | Servette FC | 4 | : | 0 |
| Group H |
Dec 14 • 18:45 | Bayer Leverkusen | | - | | Molde FK | 5 | : | 1 |
| Group H |
Dec 14 • 18:45 | Qarabağ FK | | - | | BK Häcken | 2 | : | 1 |
| Group A |
Dec 14 • 21:00 | West Ham United | | - | | SC Freiburg | 2 | : | 0 |
| Group A |
Dec 14 • 21:00 | Olympiacos CFP | | - | | FK TSC Bačka Topola | 5 | : | 2 |
| Group B |
Dec 14 • 21:00 | Ajax Amsterdam | | - | | AEK Athens | 3 | : | 1 |
| Group B |
Dec 14 • 21:00 | Brighton & Hove Albion | | - | | Olympique Marseille | 1 | : | 0 |
| Group C |
Dec 14 • 21:00 | Real Betis | | - | | Rangers FC | 2 | : | 3 |
| Group C |
Dec 14 • 21:00 | Aris Limassol | | - | | Sparta Prague | 1 | : | 3 |
| Group D |
Dec 14 • 21:00 | Sporting CP | | - | | Sturm Graz | 3 | : | 0 |
| Group D |
Dec 14 • 21:00 | Raków Częstochowa | | - | | Atalanta BC | 0 | : | 4 |
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| Feb 15 • 18:45 | Feyenoord Rotterdam |  | - | | AS Roma | 1 | : | 1 |
| Feb 15 • 18:45 | Young Boys Bern |  | - | | Sporting CP | 1 | : | 3 |
| Feb 15 • 18:45 | Galatasaray SK |  | - | | Sparta Prague | 3 | : | 2 |
| Feb 15 • 18:45 | Shakhtar Donetsk |  | - | | Olympique Marseille | 2 | : | 2 |
| Feb 15 • 21:00 | AC Milan |  | - | | Stade Rennes | 3 | : | 0 |
| Feb 15 • 21:00 | RC Lens |  | - | | SC Freiburg | 0 | : | 0 |
| Feb 15 • 21:00 | SL Benfica |  | - | | Toulouse FC | 2 | : | 1 |
| Feb 15 • 21:00 | Sporting Braga |  | - | | Qarabağ FK | 2 | : | 4 |
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| Feb 22 • 18:45 | Stade Rennes | | - | | AC Milan | 3 | : | 2 |
| Feb 22 • 18:45 | SC Freiburg | | - | | RC Lens | 3 | : | 2 |
| Feb 22 • 18:45 | Toulouse FC | | - | | SL Benfica | 0 | : | 0 |
| Feb 22 • 18:45 | Qarabağ FK | | - | | Sporting Braga | 2 | : | 3 |
| Feb 22 • 21:00 | AS Roma | | - | | Feyenoord Rotterdam | 1 | : | 1 |
| Feb 22 • 21:00 | Sporting CP | | - | | Young Boys Bern | 1 | : | 1 |
| Feb 22 • 21:00 | Sparta Prague | | - | | Galatasaray SK | 4 | : | 1 |
| Feb 22 • 21:00 | Olympique Marseille | | - | | Shakhtar Donetsk | 3 | : | 1 |
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| Mar 06 • 18:45 | Sporting CP | | - | | Atalanta BC | 1 | : | 1 |
| Mar 07 • 18:45 | AS Roma | | - | | Brighton & Hove Albion | 4 | : | 0 |
| Mar 07 • 18:45 | Sparta Prague | | - | | Liverpool FC | 1 | : | 5 |
| Mar 07 • 18:45 | Qarabağ FK | | - | | Bayer Leverkusen | 2 | : | 2 |
| Mar 07 • 21:00 | SC Freiburg | | - | | West Ham United | 1 | : | 0 |
| Mar 07 • 21:00 | SL Benfica | | - | | Rangers FC | 2 | : | 2 |
| Mar 07 • 21:00 | Olympique Marseille | | - | | Villarreal CF | 4 | : | 0 |
| Mar 07 • 21:00 | AC Milan | | - | | Slavia Prague | 4 | : | 2 |
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|
|
| Mar 14 • 18:45 | West Ham United | | - | | SC Freiburg | 5 | : | 0 |
| Mar 14 • 18:45 | Rangers FC | | - | | SL Benfica | 0 | : | 1 |
| Mar 14 • 18:45 | Villarreal CF | | - | | Olympique Marseille | 3 | : | 1 |
| Mar 14 • 18:45 | Slavia Prague | | - | | AC Milan | 1 | : | 3 |
| Mar 14 • 21:00 | Brighton & Hove Albion | | - | | AS Roma | 1 | : | 0 |
| Mar 14 • 21:00 | Atalanta BC | | - | | Sporting CP | 2 | : | 1 |
| Mar 14 • 21:00 | Liverpool FC | | - | | Sparta Prague | 6 | : | 1 |
| Mar 14 • 21:00 | Bayer Leverkusen | | - | | Qarabağ FK | 3 | : | 2 |
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| Apr 11 • 21:00 | AC Milan | | - | | AS Roma | 0 | : | 1 |
| Apr 11 • 21:00 | Liverpool FC | | - | | Atalanta BC | 0 | : | 3 |
| Apr 11 • 21:00 | Bayer Leverkusen | | - | | West Ham United | 2 | : | 0 |
| Apr 11 • 21:00 | SL Benfica | | - | | Olympique Marseille | 2 | : | 1 |
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| Apr 18 • 21:00 | AS Roma | | - | | AC Milan | 2 | : | 1 |
| Apr 18 • 21:00 | Atalanta BC | | - | | Liverpool FC | 0 | : | 1 |
| Apr 18 • 21:00 | West Ham United | | - | | Bayer Leverkusen | 1 | : | 1 |
| Apr 18 • 21:00 | Olympique Marseille | | - | | SL Benfica | 1 | : | 0 |
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| May 02 • 21:00 | Olympique Marseille | | - | | Atalanta BC | 1 | : | 1 |
| May 02 • 21:00 | AS Roma | | - | | Bayer Leverkusen | 0 | : | 2 |
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| May 09 • 21:00 | Atalanta BC | | - | | Olympique Marseille | 3 | : | 0 |
| May 09 • 21:00 | Bayer Leverkusen | | - | | AS Roma | 2 | : | 2 |
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| May 22 • 21:00 | Atalanta BC | | - | | Bayer Leverkusen | 3 | : | 0 |
