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| Pool A |
Dec 08 • 21:00 | Connacht Rugby |  | - |  | Union Bordeaux Bègles | 5 | : | 41 |
| Pool C |
Dec 08 • 21:00 | Glasgow Warriors |  | - |  | Northampton Saints | 19 | : | 28 |
| Pool C |
Dec 09 • 14:00 | RC Toulonnais |  | - |  | Exeter Chiefs | 18 | : | 19 |
| Pool B |
Dec 09 • 16:15 | Bath Rugby |  | - |  | Ulster Rugby | 37 | : | 14 |
| Pool B |
Dec 09 • 16:15 | Stade Toulousain |  | - |  | Cardiff Rugby | 52 | : | 7 |
| Pool A |
Dec 09 • 18:30 | Bulls |  | - |  | Saracens | 27 | : | 16 |
| Pool C |
Dec 09 • 18:30 | Munster Rugby |  | - |  | Aviron Bayonnais | 17 | : | 17 |
| Pool A |
Dec 09 • 21:00 | Bristol Bears |  | - |  | Lyon OU | 36 | : | 34 |
| Pool D |
Dec 10 • 14:00 | Sale Sharks |  | - |  | Stade Français | 28 | : | 5 |
| Pool D |
Dec 10 • 16:15 | Stade Rochelais |  | - |  | Leinster Rugby | 9 | : | 16 |
| Pool D |
Dec 10 • 16:15 | Leicester Tigers |  | - |  | Stormers | 35 | : | 26 |
| Pool B |
Dec 10 • 18:30 | Racing 92 |  | - |  | Harlequins | 28 | : | 31 |
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| Pool C |
Dec 15 • 21:00 | Northampton Saints | | - | | RC Toulonnais | 22 | : | 19 |
| Pool C |
Dec 15 • 21:00 | Aviron Bayonnais | | - | | Glasgow Warriors | 11 | : | 12 |
| Pool A |
Dec 16 • 14:00 | Saracens | | - | | Connacht Rugby | 55 | : | 36 |
| Pool D |
Dec 16 • 14:00 | Stormers | | - | | Stade Rochelais | 21 | : | 20 |
| Pool A |
Dec 16 • 16:15 | Union Bordeaux Bègles | | - | | Bristol Bears | 36 | : | 17 |
| Pool A |
Dec 16 • 18:30 | Lyon OU | | - | | Bulls | 29 | : | 28 |
| Pool D |
Dec 16 • 18:30 | Leinster Rugby | | - | | Sale Sharks | 37 | : | 27 |
| Pool B |
Dec 16 • 21:00 | Cardiff Rugby | | - | | Bath Rugby | 32 | : | 39 |
| Pool B |
Dec 16 • 21:00 | Ulster Rugby | | - | | Racing 92 | 31 | : | 15 |
| Pool C |
Dec 17 • 14:00 | Exeter Chiefs | | - | | Munster Rugby | 32 | : | 24 |
| Pool B |
Dec 17 • 16:15 | Harlequins | | - | | Stade Toulousain | 19 | : | 47 |
| Pool D |
Dec 17 • 18:30 | Stade Français | | - | | Leicester Tigers | 24 | : | 27 |
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| Pool C |
Jan 12 • 21:00 | Northampton Saints | | - | | Aviron Bayonnais | 61 | : | 14 |
| Pool A |
Jan 13 • 14:00 | Lyon OU | | - | | Connacht Rugby | 34 | : | 20 |
| Pool C |
Jan 13 • 14:00 | Exeter Chiefs | | - | | Glasgow Warriors | 19 | : | 17 |
| Pool A |
Jan 13 • 16:15 | Bristol Bears | | - | | Bulls | 17 | : | 31 |
| Pool C |
Jan 13 • 16:15 | RC Toulonnais | | - | | Munster Rugby | 18 | : | 29 |
| Pool D |
Jan 13 • 18:30 | Leinster Rugby | | - | | Stade Français | 43 | : | 7 |
| Pool D |
Jan 13 • 18:30 | Stormers | | - | | Sale Sharks | 31 | : | 24 |
| Pool B |
Jan 13 • 21:00 | Cardiff Rugby | | - | | Harlequins | 15 | : | 54 |
| Pool B |
Jan 13 • 21:00 | Ulster Rugby | | - | | Stade Toulousain | 24 | : | 48 |
| Pool B |
Jan 14 • 14:00 | Bath Rugby | | - | | Racing 92 | 29 | : | 25 |
| Pool D |
Jan 14 • 16:15 | Stade Rochelais | | - | | Leicester Tigers | 45 | : | 12 |
| Pool A |
Jan 14 • 18:30 | Union Bordeaux Bègles | | - | | Saracens | 55 | : | 15 |
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| Pool A |
Jan 19 • 21:00 | Connacht Rugby | | - | | Bristol Bears | 27 | : | 10 |
| Pool C |
Jan 19 • 21:00 | Glasgow Warriors | | - | | RC Toulonnais | 29 | : | 5 |
| Pool A |
Jan 20 • 14:00 | Bulls | | - | | Union Bordeaux Bègles | 46 | : | 40 |
| Pool B |
Jan 20 • 14:00 | Harlequins | | - | | Ulster Rugby | 47 | : | 19 |
| Pool B |
Jan 20 • 16:15 | Racing 92 | | - | | Cardiff Rugby | 48 | : | 26 |
| Pool D |
Jan 20 • 16:15 | Leicester Tigers | | - | | Leinster Rugby | 10 | : | 27 |
| Pool C |
Jan 20 • 18:30 | Munster Rugby | | - | | Northampton Saints | 23 | : | 26 |
| Pool D |
Jan 20 • 18:30 | Stade Français | | - | | Stormers | 20 | : | 24 |
| Pool A |
Jan 20 • 21:00 | Saracens | | - | | Lyon OU | 39 | : | 24 |
| Pool D |
Jan 21 • 14:00 | Sale Sharks | | - | | Stade Rochelais | 24 | : | 37 |
| Pool B |
Jan 21 • 16:15 | Stade Toulousain | | - | | Bath Rugby | 31 | : | 19 |
| Pool C |
Jan 21 • 18:30 | Aviron Bayonnais | | - | | Exeter Chiefs | 40 | : | 17 |
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| Apr 05 • 21:00 | Harlequins | | - | | Glasgow Warriors | 28 | : | 24 |
| Apr 06 • 13:30 | Bulls | | - | | Lyon OU | 59 | : | 19 |
| Apr 06 • 16:00 | Exeter Chiefs | | - | | Bath Rugby | 21 | : | 15 |
| Apr 06 • 16:00 | Stormers | | - | | Stade Rochelais | 21 | : | 22 |
| Apr 06 • 18:30 | Union Bordeaux Bègles | | - | | Saracens | 45 | : | 12 |
| Apr 06 • 21:00 | Leinster Rugby | | - | | Leicester Tigers | 36 | : | 22 |
| Apr 07 • 13:30 | Northampton Saints | | - | | Munster Rugby | 24 | : | 14 |
| Apr 07 • 16:00 | Stade Toulousain | | - | | Racing 92 | 31 | : | 7 |
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| Apr 13 • 16:00 | Union Bordeaux Bègles | | - | | Harlequins | 41 | : | 42 |
| Apr 13 • 18:30 | Leinster Rugby | | - | | Stade Rochelais | 40 | : | 13 |
| Apr 13 • 21:00 | Northampton Saints | | - | | Bulls | 59 | : | 22 |
| Apr 14 • 16:00 | Stade Toulousain | | - | | Exeter Chiefs | 64 | : | 26 |
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| May 04 • 18:30 | Leinster Rugby | | - | | Northampton Saints | 20 | : | 17 |
| May 05 • 16:00 | Stade Toulousain | | - | | Harlequins | 38 | : | 26 |
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| May 25 • 15:45 | Leinster Rugby | | - | | Stade Toulousain | 22 | : | 31 |
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