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| Oct 13 • 20:45 | Bristol Bears |  | - |  | Leicester Tigers | 25 | : | 14 |
| Oct 14 • 14:30 | Exeter Chiefs |  | - |  | Saracens | 65 | : | 10 |
| Oct 14 • 15:00 | Bath Rugby |  | - |  | Newcastle Falcons | 34 | : | 26 |
| Oct 14 • 15:00 | Gloucester Rugby |  | - |  | Harlequins | 29 | : | 28 |
| Oct 15 • 14:30 | Sale Sharks |  | - |  | Northampton Saints | 20 | : | 15 |
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| Oct 20 • 19:00 | Newcastle Falcons | | - | | Gloucester Rugby | 14 | : | 18 |
| Oct 21 • 16:00 | Saracens | | - | | Bath Rugby | 16 | : | 25 |
| Oct 21 • 16:00 | Northampton Saints | | - | | Bristol Bears | 27 | : | 33 |
| Oct 21 • 16:05 | Leicester Tigers | | - | | Sale Sharks | 17 | : | 24 |
| Oct 22 • 16:00 | Harlequins | | - | | Exeter Chiefs | 22 | : | 14 |
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| Oct 27 • 20:45 | Gloucester Rugby | | - | | Saracens | 3 | : | 24 |
| Oct 28 • 15:30 | Bristol Bears | | - | | Harlequins | 21 | : | 23 |
| Oct 28 • 16:00 | Exeter Chiefs | | - | | Sale Sharks | 43 | : | 0 |
| Oct 28 • 16:05 | Bath Rugby | | - | | Leicester Tigers | 24 | : | 25 |
| Oct 29 • 16:00 | Newcastle Falcons | | - | | Northampton Saints | 14 | : | 16 |
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| Nov 03 • 20:45 | Sale Sharks | | - | | Gloucester Rugby | 24 | : | 10 |
| Nov 04 • 16:00 | Harlequins | | - | | Newcastle Falcons | 40 | : | 12 |
| Nov 04 • 16:00 | Northampton Saints | | - | | Bath Rugby | 24 | : | 18 |
| Nov 04 • 16:05 | Saracens | | - | | Leicester Tigers | 32 | : | 17 |
| Nov 05 • 16:00 | Exeter Chiefs | | - | | Bristol Bears | 29 | : | 20 |
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| Nov 10 • 20:45 | Gloucester Rugby | | - | | Bath Rugby | 27 | : | 45 |
| Nov 11 • 15:30 | Bristol Bears | | - | | Sale Sharks | 13 | : | 27 |
| Nov 11 • 16:05 | Leicester Tigers | | - | | Harlequins | 25 | : | 29 |
| Nov 12 • 16:00 | Newcastle Falcons | | - | | Saracens | 12 | : | 50 |
| Nov 12 • 16:00 | Northampton Saints | | - | | Exeter Chiefs | 34 | : | 19 |
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| Nov 17 • 20:45 | Sale Sharks | | - | | Newcastle Falcons | 40 | : | 22 |
| Nov 17 • 20:45 | Bath Rugby | | - | | Bristol Bears | 20 | : | 19 |
| Nov 18 • 16:05 | Leicester Tigers | | - | | Northampton Saints | 26 | : | 17 |
| Nov 18 • 18:30 | Harlequins | | - | | Saracens | 10 | : | 38 |
| Nov 19 • 16:00 | Exeter Chiefs | | - | | Gloucester Rugby | 25 | : | 24 |
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| Nov 24 • 20:45 | Sale Sharks | | - | | Bath Rugby | 11 | : | 9 |
| Nov 24 • 20:45 | Northampton Saints | | - | | Harlequins | 36 | : | 33 |
| Nov 25 • 15:30 | Gloucester Rugby | | - | | Leicester Tigers | 20 | : | 38 |
| Nov 25 • 16:00 | Saracens | | - | | Bristol Bears | 39 | : | 31 |
| Nov 26 • 16:00 | Newcastle Falcons | | - | | Exeter Chiefs | 14 | : | 20 |
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| Dec 01 • 20:45 | Harlequins | | - | | Sale Sharks | 36 | : | 3 |
| Dec 02 • 15:00 | Bristol Bears | | - | | Gloucester Rugby | 51 | : | 26 |
| Dec 02 • 16:00 | Bath Rugby | | - | | Exeter Chiefs | 41 | : | 24 |
| Dec 02 • 17:30 | Saracens | | - | | Northampton Saints | 12 | : | 18 |
| Dec 03 • 16:00 | Leicester Tigers | | - | | Newcastle Falcons | 47 | : | 3 |
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| Dec 22 • 20:45 | Newcastle Falcons | | - | | Bristol Bears | 13 | : | 21 |
| Dec 22 • 20:45 | Sale Sharks | | - | | Saracens | 22 | : | 20 |
| Dec 23 • 16:00 | Gloucester Rugby | | - | | Northampton Saints | 29 | : | 31 |
| Dec 23 • 16:00 | Exeter Chiefs | | - | | Leicester Tigers | 29 | : | 10 |
| Dec 23 • 16:05 | Bath Rugby | | - | | Harlequins | 25 | : | 17 |
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| Dec 29 • 20:45 | Bristol Bears | | - | | Exeter Chiefs | 14 | : | 24 |
| Dec 30 • 16:00 | Saracens | | - | | Newcastle Falcons | 37 | : | 19 |
| Dec 30 • 16:05 | Northampton Saints | | - | | Sale Sharks | 21 | : | 17 |
| Dec 30 • 18:30 | Harlequins | | - | | Gloucester Rugby | 32 | : | 26 |
| Dec 31 • 16:00 | Leicester Tigers | | - | | Bath Rugby | 35 | : | 22 |
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| Jan 05 • 20:45 | Sale Sharks | | - | | Bristol Bears | 14 | : | 22 |
| Jan 05 • 20:45 | Newcastle Falcons | | - | | Harlequins | 3 | : | 24 |
| Jan 06 • 16:00 | Exeter Chiefs | | - | | Northampton Saints | 36 | : | 42 |
| Jan 06 • 16:05 | Leicester Tigers | | - | | Saracens | 19 | : | 10 |
| Jan 07 • 16:00 | Bath Rugby | | - | | Gloucester Rugby | 17 | : | 10 |
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| Jan 26 • 20:45 | Harlequins | | - | | Leicester Tigers | 19 | : | 20 |
| Jan 27 • 15:00 | Northampton Saints | | - | | Newcastle Falcons | 38 | : | 13 |
| Jan 27 • 16:05 | Bristol Bears | | - | | Bath Rugby | 57 | : | 44 |
| Jan 27 • 18:30 | Saracens | | - | | Exeter Chiefs | 40 | : | 22 |
| Jan 28 • 16:00 | Gloucester Rugby | | - | | Sale Sharks | 32 | : | 20 |
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| Mar 22 • 20:45 | Bristol Bears | | - | | Northampton Saints | 52 | : | 21 |
| Mar 22 • 20:45 | Leicester Tigers | | - | | Gloucester Rugby | 25 | : | 27 |
| Mar 23 • 16:00 | Exeter Chiefs | | - | | Newcastle Falcons | 25 | : | 16 |
| Mar 23 • 16:05 | Saracens | | - | | Harlequins | 52 | : | 7 |
| Mar 24 • 16:00 | Bath Rugby | | - | | Sale Sharks | 42 | : | 24 |
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| Mar 29 • 20:45 | Newcastle Falcons | | - | | Leicester Tigers | 13 | : | 19 |
| Mar 29 • 20:45 | Northampton Saints | | - | | Saracens | 41 | : | 30 |
| Mar 30 • 16:00 | Gloucester Rugby | | - | | Bristol Bears | 24 | : | 33 |
| Mar 30 • 16:05 | Harlequins | | - | | Bath Rugby | 40 | : | 36 |
| Mar 31 • 16:00 | Sale Sharks | | - | | Exeter Chiefs | 41 | : | 5 |
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| Apr 20 • 16:00 | Saracens | | - | | Gloucester Rugby | 46 | : | 24 |
| Apr 20 • 16:05 | Northampton Saints | | - | | Leicester Tigers | 40 | : | 17 |
| Apr 20 • 18:30 | Exeter Chiefs | | - | | Bath Rugby | 14 | : | 26 |
| Apr 21 • 16:00 | Sale Sharks | | - | | Harlequins | 37 | : | 31 |
| Apr 21 • 16:00 | Bristol Bears | | - | | Newcastle Falcons | 85 | : | 14 |
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| Apr 26 • 20:45 | Bath Rugby | | - | | Saracens | 12 | : | 15 |
| Apr 27 • 16:00 | Leicester Tigers | | - | | Bristol Bears | 19 | : | 21 |
| Apr 27 • 16:05 | Harlequins | | - | | Northampton Saints | 41 | : | 32 |
| Apr 28 • 16:00 | Newcastle Falcons | | - | | Sale Sharks | 14 | : | 35 |
| Apr 28 • 16:00 | Gloucester Rugby | | - | | Exeter Chiefs | 17 | : | 38 |
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| May 10 • 20:45 | Newcastle Falcons | | - | | Bath Rugby | 17 | : | 28 |
| May 10 • 20:45 | Sale Sharks | | - | | Leicester Tigers | 31 | : | 22 |
| May 11 • 16:05 | Bristol Bears | | - | | Saracens | 20 | : | 41 |
| May 11 • 16:05 | Northampton Saints | | - | | Gloucester Rugby | 90 | : | 0 |
| May 11 • 18:30 | Exeter Chiefs | | - | | Harlequins | 58 | : | 26 |
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| May 18 • 16:05 | Saracens | | - | | Sale Sharks | 10 | : | 20 |
| May 18 • 16:05 | Bath Rugby | | - | | Northampton Saints | 43 | : | 12 |
| May 18 • 16:05 | Gloucester Rugby | | - | | Newcastle Falcons | 54 | : | 14 |
| May 18 • 16:05 | Harlequins | | - | | Bristol Bears | 28 | : | 53 |
| May 18 • 16:05 | Leicester Tigers | | - | | Exeter Chiefs | 40 | : | 22 |
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| May 31 • 20:45 | Northampton Saints | | - | | Saracens | 22 | : | 20 |
| Jun 01 • 16:30 | Bath Rugby | | - | | Sale Sharks | 31 | : | 23 |
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| Jun 08 • 16:00 | Northampton Saints | | - | | Bath Rugby | 25 | : | 21 |
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